Evidence map›Paper›PMID 35624448›Full record

Observational studyBMC pediatrics2022

Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children.

Loo Wee Chia, Thi Viet Ha Nguyen, Van Nha Phan, Thi Thao Nguyen Luu, Gia Khanh Nguyen, Serene Yaling Tan, Shaman Rajindrajith, Marc Alexander Benninga

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Functional Diarrhea in Children.Indian journal of pediatrics · 2024
    Review
  8. Prevalence of functional gastrointestinal disorders in Saudi infants and toddlers: A cross-sectional multicenter study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Prevalence, Risk Factors, and Pediatrician Awareness of Infant Dyschezia in Indonesia.Pediatric gastroenterology, hepatology & nutrition · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Loo Wee Chia *FrieslandCampina, Amersfoort, The Netherlands. loo-wee@hotmail.com.
Thi Viet Ha Nguyen *Department of Paediatrics, Hanoi Medical University, Hanoi, Vietnam.
Van Nha PhanDepartment of Paediatrics, Hanoi Medical University, Hanoi, Vietnam.
Thi Thao Nguyen LuuDepartment of Paediatrics, Hanoi Medical University, Hanoi, Vietnam.
Gia Khanh NguyenNational Paediatric Association Vietnam, Hanoi, Vietnam.
Serene Yaling TanFrieslandCampina, Amersfoort, The Netherlands.
Shaman RajindrajithDepartment of Paediatrics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Marc Alexander BenningaDepartment of Paediatric Gastroenterology, Emma Children's Hospital, Amsterdam University Medical Centres, Amsterdam, 1105, AZ, The Netherlands.
Hanoi Medical University · VNFrieslandCampina (Netherlands) · NLEmma Kinderziekenhuis · NLUniversity of Colombo · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional gastrointestinal disorders (FGIDs) are common early in life. The prevalence of FGIDs varies among countries but is unknown in Vietnam. The aim of this study is to assess the prevalence of FGIDs in healthy Vietnamese infants and young children.

methodsThis was a cross-sectional, observational study involving healthy infants and young children between 0 - 48 months old in Hanoi, Vietnam. A representative total of 1511 subjects completed the validated questionnaire on paediatric FGIDs. Rome IV criteria were used to define FGIDs.

resultsFor Vietnamese infants (0-6 months) and young children (7-48 months), the prevalence of having at least one FGID was 10.0% and only 0.6% was having more than one FGID. Infantile regurgitation (9.3%) was the most prevalent FGID among infants 0-6 months of age while all other FGIDs had a low prevalence between 0-2.5%. For young children between 7 - 48 months old, functional constipation was the most common disorder at the rate of 5.6%. Association analysis revealed that the risk of infant regurgitation was significantly lower among infants with exclusively breastfeeding at 2 - 3 months and 3 - 4 months, formula initiation at 0 - 1 months, and higher paternal education level. The prevalence of functional constipation was significantly higher in male subjects, children in families with annual household income between 273,000,000 - 546,999,999 VND (or estimate around 11,800 - 23,800 USD), families with one child only, and formula feeding initiation at 1 - 2 months.

conclusionsThe prevalence of FGIDs in Vietnamese infants and young children is relatively low compared to the published literature using Rome IV diagnostic criteria. Infantile regurgitation was the most common FGID in Vietnamese infants while functional constipation was most prevalent among Vietnamese young children.

trial registrationNetherlands Trial Registry Identifier: NL7286/NTR7495 .

Indexed as

Gastrointestinal DiseasesAsian PeopleChildChild, PreschoolConstipationCross-Sectional StudiesFathersFemaleHumansInfantInfant, NewbornMalePrevalenceRisk FactorsVietnamVomitingColicConstipationDiarrhoeaDyscheziaPaediatricRegurgitationRome IVToddler

Identifiers

PMID35624448
PMCPMC9137065
OpenAlexW4281613803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.