Evidence map›Paper›PMID 35624355›Full record

ArticleJournal of molecular neuroscience : MN2022

NKCC1 to KCC2 mRNA Ratio in Schizophrenia and Its Psychopathology: a Case-Control Study.

Hoorie Mohaghghegh, Esmaeil Shahsavand Ananloo, Mahmoudreza Hadjighasem, Morteza Karimipour, Shiva Hashemizadeh, Seyyed Ali Ahmadi Abhari

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hoorie MohaghgheghDepartment of Neuroscience and Addiction Study, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-6704-9819
Esmaeil Shahsavand AnanlooDepartment of Neuroscience and Addiction Study, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. shahsavand@sina.tums.ac.ir.ORCID http://orcid.org/0000-0003-0768-7207
Mahmoudreza HadjighasemDepartment of Neuroscience and Addiction Study, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. mhadjighassem@tums.ac.ir.ORCID http://orcid.org/0000-0001-9046-2767
Morteza KarimipourBiotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0002-2406-5963
Shiva HashemizadehDepartment of Neuroscience and Addiction Study, School of Advanced Technologies in Medicine, International Campus, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-1223-2688
Seyyed Ali Ahmadi AbhariDepartment of Psychiatry, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Tehran University of Medical Sciences · IRPasteur Institute of Iran · IRShahed University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia (SCZ) is a debilitating, destructive, and chronic mental disorder and affects approximately one percent of the human population. Diagnosis in psychiatry is based on the patient's descriptions of his/her symptoms, interviewer's observations, history of disorder over time, and response to treatment. All of these data measure phenotype-based functions. But it appears that accurate diagnosis of such a complex disorder must be based on valid and reliable factors. In the present study, gene selection was based on the possible role of γ-aminobutyric acid (GABA) in psychopathology of SCZ and expression in blood. We evaluated the association of Na

Indexed as

SchizophreniaSolute Carrier Family 12, Member 2SymportersCase-Control StudiesFemaleHumansK Cl- CotransportersMaleRNA, MessengerK Cl- CotransportersRNA, MessengerSLC12A2 protein, humanSLC12A5 protein, humanSolute Carrier Family 12, Member 2SymportersGeneKCC2mRNANKCC1PANSSSchizophrenia

Identifiers

PMID35624355
OpenAlexW4281763612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.