Evidence map›Paper›PMID 35624175›Full record

ArticleBreast cancer research and treatment2022

Breast cancer diagnosis and treatment during the COVID-19 pandemic in a nationwide, insured population.

Jennifer L Caswell-Jin, Maryam N Shafaee, Lan Xiao, Mina Liu, Esther M John, Melissa L Bondy, Allison W Kurian

Open access · bronzeAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

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  11. The impact of the COVID-19 pandemic on clinical staging, pathological staging and surgical management of breast cancer patients.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
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  12. Article
  13. Impact on the Volume of Pathology Reports Before and During the COVID-19 Pandemic in SEER Cancer Registries.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jennifer L Caswell-Jin *Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. caswell@stanford.edu.ORCID http://orcid.org/0000-0002-5711-8355
Maryam N Shafaee *Dan L Duncan Cancer, Baylor College of Medicine, Houston, TX, USA.
Lan XiaoDepartment of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.
Mina LiuDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Esther M JohnDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Melissa L Bondy *Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.
Allison W Kurian *Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Stanford University · USBaylor College of Medicine · USStanford Medicine · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Melinda L. Telli · 2007 to 2026
$71.4M
NCI NIH HHS P30 CA124435
6 · The paper itself

Abstract

purposeThe early months of the COVID-19 pandemic led to reduced cancer screenings and delayed cancer surgeries. We used insurance claims data to understand how breast cancer incidence and treatment after diagnosis changed nationwide over the course of the pandemic.

methodsUsing the Optum Research Database from January 2017 to March 2021, including approximately 19 million US adults with commercial health insurance, we identified new breast cancer diagnoses and first treatment after diagnosis. We compared breast cancer incidence and proportion of newly diagnosed patients receiving pre-operative systemic therapy pre-COVID, in the first 2 months of the COVID pandemic and in the later part of the COVID pandemic.

resultsAverage monthly breast cancer incidence was 19.3 (95% CI 19.1-19.5) cases per 100,000 women and men pre-COVID, 11.6 (95% CI 10.8-12.4) per 100,000 in April-May 2020, and 19.7 (95% CI 19.3-20.1) per 100,000 in June 2020-February 2021. Use of pre-operative systemic therapy was 12.0% (11.7-12.4) pre-COVID, 37.7% (34.9-40.7) for patients diagnosed March-April 2020, and 14.8% (14.0-15.7) for patients diagnosed May 2020-January 2021. The changes in breast cancer incidence across the pandemic did not vary by demographic factors. Use of pre-operative systemic therapy across the pandemic varied by geographic region, but not by area socioeconomic deprivation or race/ethnicity.

conclusionIn this US-insured population, the dramatic changes in breast cancer incidence and the use of pre-operative systemic therapy experienced in the first 2 months of the pandemic did not persist, although a modest change in the initial management of breast cancer continued.

Indexed as

Breast NeoplasmsCOVID-19AdultEarly Detection of CancerFemaleHumansInsurance, HealthMalePandemicsBreast cancer incidenceCOVID-19Insurance claimsNeoadjuvant endocrinePreoperative endocrine

Identifiers

PMID35624175
PMCPMC9140322
OpenAlexW4281654959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.