Evidence map›Paper›PMID 35624150›Full record

ReviewNature biomedical engineering2022

Criteria for the design of tissue-mimicking phantoms for the standardization of biophotonic instrumentation.

Lina Hacker, Heidrun Wabnitz, Antonio Pifferi, T Joshua Pfefer, Brian W Pogue, Sarah E Bohndiek

Abstract readReview
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In one paragraph

Review in Nature biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lina HackerDepartment of Physics, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5160-0952
Heidrun WabnitzPhysikalisch-Technische Bundesanstalt (PTB), Berlin, Germany.ORCID http://orcid.org/0000-0002-3846-8659
Antonio PifferiDepartment of Physics, Politecnico di Milano, Milan, Italy.
T Joshua PfeferUS Food and Drug Administration, Silver Spring, MD, USA.
Brian W PogueThayer School of Engineering, Dartmouth, Hanover, NH, USA.ORCID http://orcid.org/0000-0002-9887-670X
Sarah E BohndiekDepartment of Physics, University of Cambridge, Cambridge, UK. seb53@cam.ac.uk.ORCID http://orcid.org/0000-0003-0371-8635

Funding

Cancer Research UK 16267Cancer Research UK C47594/A16267Cancer Research UK C9545/A29580
6 · The paper itself

Abstract

A lack of accepted standards and standardized phantoms suitable for the technical validation of biophotonic instrumentation hinders the reliability and reproducibility of its experimental outputs. In this Perspective, we discuss general criteria for the design of tissue-mimicking biophotonic phantoms, and use these criteria and state-of-the-art developments to critically review the literature on phantom materials and on the fabrication of phantoms. By focusing on representative examples of standardization in diffuse optical imaging and spectroscopy, fluorescence-guided surgery and photoacoustic imaging, we identify unmet needs in the development of phantoms and a set of criteria (leveraging characterization, collaboration, communication and commitment) for the standardization of biophotonic instrumentation.

Indexed as

Research DesignSurgery, Computer-AssistedReference StandardsReproducibility of Results

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.