Evidence map›Paper›PMID 35624097›Full record

ArticleLight, science & applications2022

Bringing chiral functionality to in vivo applications of nanomaterials.

Maria Mukhina

Abstract read
In one paragraph

Article in Light, science & applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Maria MukhinaDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA. mmukhina@fas.harvard.edu.ORCID http://orcid.org/0000-0001-9656-1221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chirality is a universal property of an endless number of objects in the universe. Nanotechnology is rapidly expanding to find ways to introduce chirality to artificial nanostructures. In a recent publication in Light: Science and Applications, Das et al. have successfully used capping with chiral ligand molecules to obtain chiral carbon dots. The authors provide a theoretical model to describe the origin of chirality in carbon dots as arising due to exciton coupling in a pair of chiral chromophores. Due to non-toxic chemical composition and sizes as small as 2-5 nm, the chiral carbon dots have the potential to outperform other chiral nanostructures in numerous biomedical applications. However, similarly to chiral drugs, their chiral toxicity must be well understood before the carbon dots are brought to living systems.

Identifiers

PMID35624097
PMCPMC9142540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.