Evidence map›Paper›PMID 35623860›Full record

ArticleClinical nutrition ESPEN2022

Dairy product consumption and calcified atherosclerotic plaques in the coronary arteries: The NHLBI Family Heart Study.

Ulf Neisius, Guohai Zhou, Rachel E Ward, R Curtis Ellison, J Michael Gaziano, Luc Djoussé

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical nutrition ESPEN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ulf NeisiusCardiology Section, Department of Medicine, VA Boston Healthcare System, Harvard Medical School, Boston, MA, USA; Division of Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: ulf.neisius@va.gov.
Guohai ZhouCenter for Clinical Investigation, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Rachel E WardMassachusetts Veterans Epidemiology and Research Information Center (MAVERIC) Boston, VA Boston Healthcare System, Boston, MA, USA.
R Curtis EllisonSection of Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
J Michael GazianoCardiology Section, Department of Medicine, VA Boston Healthcare System, Harvard Medical School, Boston, MA, USA; Division of Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Massachusetts Veterans Epidemiology and Research Information Center (MAVERIC) Boston, VA Boston Healthcare System, Boston, MA, USA.
Luc DjousséDivision of Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Massachusetts Veterans Epidemiology and Research Information Center (MAVERIC) Boston, VA Boston Healthcare System, Boston, MA, USA; Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Brigham and Women's Hospital · USBoston University · USVA Boston Healthcare System · US

Funding

Effects of Vitamin D and Omega 3 Fatty Acids on Incidence Rate of Heart FailureR01HL131687 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DJOUSSE, LUC · 2017 to 2020
$2.7M
GENCAC-Data Coordinating CenterU01HL067899 · NHLBI · WASHINGTON UNIVERSITY · PI PROVINCE, MICHAEL A · 2001 to 2004
$1.4M
GENCAC - Utah Field CenterU01HL067894 · NHLBI · UNIVERSITY OF UTAH · PI HUNT, STEVEN C. · 2001 to 2004
$1.3M
GENCAC - Arterial Calcium Reading CenterU01HL067897 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CARR, JOHN JEFFREY · 2001 to 2004
$1.2M
GENCAC - Minnesota Field CenterU01HL067901 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PANKOW, JAMES S · 2001 to 2004
$1.1M
GENCAC - Birmingham Field CenterU01HL067898 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 2001 to 2004
$1.0M
GENCAC - MOLECULAR GENETICS LABORATORYU01HL067902 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HIXSON, JAMES E. · 2001 to 2004
$1.0M
GENCAC - North Carolina Field CenterU01HL067895 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WAGENKNECHT, LYNNE E · 2001 to 2004
$989k
GENCAC - Framingham Field CenterU01HL067896 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ELLISON, CURTIS R. · 2001 to 2004
$971k
GENCAC - CENTRAL BIOCHEMISTRY LABORATORYU01HL067900 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ECKFELDT, JOHN H · 2001 to 2004
$884k
Genetics of Coronary and Aortic Calcification (GENCAC)U01HL067893 · NHLBI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI HEISS, GERARDO · 2001 to 2004
$818k
NHLBI NIH HHS R01 HL131687NHLBI NIH HHS U01 HL067893NHLBI NIH HHS U01 HL067894NHLBI NIH HHS U01 HL067895NHLBI NIH HHS U01 HL067896NHLBI NIH HHS U01 HL067897NHLBI NIH HHS U01 HL067898NHLBI NIH HHS U01 HL067899NHLBI NIH HHS U01 HL067900NHLBI NIH HHS U01 HL067901NHLBI NIH HHS U01 HL067902
6 · The paper itself

Abstract

BACKGROUND &

aimsDiet modification is a major component of non-pharmacological coronary heart disease (CHD) prevention. Few studies have examined the association between consumption of different dairy products with subclinical coronary artery disease. We sought to examine whether milk, yogurt, or cheese consumption is associated with calcified atherosclerotic plaques in the coronary arteries.

methodsWe cross-sectionally examined 2278 participants from the National Heart, Lung, and Blood Institute Family Heart Study. Dairy consumption was assessed by a semiquantitative food frequency questionnaire. Coronary artery calcium (CAC) was estimated by cardiac computed tomography. We used an Agatston score of ≥100 to indicate prevalent CAC and fitted multivariable logistic regression to calculate adjusted odds ratios.

resultsMean age was 58 ± 13 years and 45% were male. The frequency of milk (≤1/week, 2-4/week, and ≥5/week; 22%, 14%, and 64%, respectively), yogurt (almost never, <1/week, and ≥1/week; 54%, 20%, and 26%, respectively), and cheese consumption (<1/week, 1/week, 2-4/week, and ≥5/week; 15%, 17%, 41%, and 27%, respectively) varied in the cohort. We observed an inverse association of cheese consumption with prevalent CAC: odds ratio (95% CI) of 0.63 (0.42-0.94) when comparing cheese intake of ≥5 servings/week with <1/week, adjusting for sex, age, body mass index, cigarette pack years, presence of CHD, family income, and education (p for linear trend 0.007). In contrast, there was no association between yogurt or milk consumption and CAC (p for linear trend 0.51 and 0.87, respectively).

conclusionOur data suggest that cheese consumption but not yogurt or milk is associated with a lower odds of CAC in men and women.

Indexed as

Coronary Artery DiseasePlaque, AtheroscleroticAgedAnimalsCalciumFemaleHeartHumansMaleMiddle AgedMilkNational Heart, Lung, and Blood Institute (U.S.)United StatesCalciumCheeseCoronary artery calcium scoreCoronary artery diseaseDairy consumptionMilkYogurt

Identifiers

PMID35623860
PMCPMC9142774
OpenAlexW4214548265

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.