Evidence map›Paper›PMID 35623845›Full record

ArticleClinical nutrition ESPEN2022

Body mass index and its association with COVID-19 clinical outcomes: Findings from the Philippine CORONA study.

Adrian I Espiritu, Nikolai Gil D Reyes, Carl Froilan D Leochico, Marie Charmaine C Sy, Emilio Q Villanueva Iii, Veeda Michelle M Anlacan, Roland Dominic G Jamora

Abstract readMulticenter Study
In one paragraph

Article in Clinical nutrition ESPEN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. How Filipinos View Obesity: Findings From the ACTION APAC Study.Journal of the ASEAN Federation of Endocrine Societies · 2026
    Article
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  10. Incidence and risk factors for stroke in patients with COVID-19 in the Philippines: An analysis of 10,881 cases.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrian I EspirituDivision of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Department of Clinical Epidemiology, College of Medicine, University of the Philippines Manila, Manila, Philippines; Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, ON M5B 1W8, Canada. Electronic address: aiespiritu@up.edu.ph.
Nikolai Gil D ReyesDivision of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Electronic address: ndreyes@up.edu.ph.
Carl Froilan D LeochicoDepartment of Rehabilitation Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Department of Physical Medicine and Rehabilitation, St. Luke's Medical Center, Quezon City and Global City, Philippines. Electronic address: cdleochico@up.edu.ph.
Marie Charmaine C SyDivision of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Electronic address: mcsy2@up.edu.ph.
Emilio Q Villanueva IiiDepartment of Pathology, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Philippines. Electronic address: eqvillanueva@up.edu.ph.
Veeda Michelle M AnlacanDivision of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Electronic address: vmanlacan@up.edu.ph.
Roland Dominic G JamoraDivision of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Institute for Neurosciences, St. Luke's Medical Center, Quezon City & Global City, Philippines. Electronic address: rgjamora@up.edu.ph.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsTo explore the association between body mass index (BMI) and adverse outcomes in a large cohort of patients with coronavirus disease 2019 (COVID-19).

methodsThis is a secondary analysis of a 37-site, nationwide, multicenter, retrospective cohort study that investigated the clinical and neurological outcomes of adult patients with confirmed COVID-19 admitted from February to December 15, 2020.

resultsWe analyzed 4,463 patients with BMI and outcome data. A total of 790 (17.7%) and 710 (15.9%) had the primary outcome of in-hospital mortality and need for invasive mechanical ventilation (IMV), respectively. There was no significant association between WHO BMI groups and these outcomes. Using Asia-Pacific cutoffs showed a significant association between obesity and in-hospital mortality risk (P = 0.012). Being underweight was an independent predictor of prolonged IMV requirement regardless of BMI criteria used (P < 0.01). Obesity correlated with the need for intensive care unit admission using Asia-Pacific cutoffs (P = 0.029). There was a significant association between any BMI abnormality and odds of severe/critical COVID-19 (P < 0.05). Obese patients with concomitant acute neurological presentation/diagnosis during their COVID-19 admission were shown to have lower odds of neurologic recovery (P < 0.05).

conclusionsWe found BMI abnormalities to be associated with several adverse clinical and neurologic outcomes, although such associations may be more evident with the use of race-specific BMI criteria.

Indexed as

COVID-19AdultBody Mass IndexHumansObesityPhilippinesRetrospective StudiesBody mass indexCOVID-19ObesityOutcomesSARS-CoV-2Underweight

Identifiers

PMID35623845
PMCPMC8968152

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.