Evidence map›Paper›PMID 35623653›Full record

ArticleBMJ case reports2022

B cell depletion therapy using rituximab to induce long-term remission of recalcitrant skin lesions of subacute cutaneous lupus erythematosus.

Nikhil Mehta, Narayanan Baskaran, Sudheer Arava, Somesh Gupta

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikhil MehtaDepartment of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.ORCID http://orcid.org/0000-0002-1735-1494
Narayanan BaskaranDepartment of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Sudheer AravaDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, New Delhi, Delhi, India.
Somesh GuptaDepartment of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India someshgupta@aiims.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman in her 20s presented with chilblains for 2 years and recent-onset photodistributed psoriasiform plaques. She did not have persistent good improvement despite treatment with 1 mg/kg oral prednisolone, along with successive trials with many steroid-sparing adjuvants in adequate dosage and duration, including hydroxychloroquine, methotrexate and cyclosporine, in the following 6 months. The patient had an excellent improvement and went into remission with two doses of injection rituximab, 1 g each, at a 2-week interval. The remission was maintained during the 14-month follow-up.

Indexed as

ChilblainsLupus Erythematosus, CutaneousCyclosporineFemaleHumansHydroxychloroquineRituximabCyclosporineHydroxychloroquineRituximabDermatologySkin

Identifiers

PMID35623653
PMCPMC9150159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.