Evidence map›Paper›PMID 35623573›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2022

Responses of reconstituted human bronchial epithelia from normal and health-compromised donors to non-volatile particulate matter emissions from an aircraft turbofan engine.

Mathilde N Delaval, Hulda R Jonsdottir, Zaira Leni, Alejandro Keller, Benjamin T Brem, Frithjof Siegerist, David Schönenberger, Lukas Durdina, Miriam Elser, Matthias Salathe and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Application of the market-ready NAVETTA electrodeposition chamber for controlledComputational and structural biotechnology journal · 2025
    Article
  3. Article
  4. Toward Elimination of Soot Emissions from Jet Fuel Combustion.Environmental science & technology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Mathilde N DelavalInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Hulda R JonsdottirInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Zaira LeniInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland.
Alejandro KellerInstitute for Sensors and Electronics, University of Applied Sciences and Arts Northwestern Switzerland, 5210 Windisch, Switzerland.
Benjamin T BremEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies, 8600 Dübendorf, Switzerland.
Frithjof SiegeristSR Technics, 8302, Kloten, Switzerland.
David SchönenbergerEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies, 8600 Dübendorf, Switzerland.
Lukas DurdinaEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies, 8600 Dübendorf, Switzerland.
Miriam ElserEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies, 8600 Dübendorf, Switzerland; Empa, Swiss Federal Laboratories for Materials Science and Technology, Automotive Powertrain Technologies Laboratory, 8600 Dübendorf, Switzerland.
Matthias SalatheDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Nathalie BaumlinDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Prem LoboMetrology Research Centre, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada.
Heinz BurtscherInstitute for Sensors and Electronics, University of Applied Sciences and Arts Northwestern Switzerland, 5210 Windisch, Switzerland.
Anthi LiatiEmpa, Swiss Federal Laboratories for Materials Science and Technology, Automotive Powertrain Technologies Laboratory, 8600 Dübendorf, Switzerland.
Marianne GeiserInstitute of Anatomy, University of Bern, 3012 Bern, Switzerland. Electronic address: marianne.geiser@unibe.ch.
Swiss Federal Laboratories for Materials Science and Technology · CHUniversity of Bern · CHFHNW University of Applied Sciences and Arts · CHUniversity of Kansas Medical Center · USNational Research Council Canada · CA

Funding

Anti-inflammatory therapy to augment CFTR rescue in CF patientsR01HL133240 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SALATHE, MATTHIAS A · 2017 to 2020
$2.7M
Mechanisms of mucociliary dysfunction in cystic fibrosis related diabetesR01HL157942 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KIM, MICHAEL D, SALATHE, MATTHIAS A · 2021 to 2024
$2.7M
NHLBI NIH HHS R01 HL133240NHLBI NIH HHS R01 HL157942
6 · The paper itself

Abstract

Health effects of particulate matter (PM) from aircraft engines have not been adequately studied since controlled laboratory studies reflecting realistic conditions regarding aerosols, target tissue, particle exposure and deposited particle dose are logistically challenging. Due to the important contributions of aircraft engine emissions to air pollution, we employed a unique experimental setup to deposit exhaust particles directly from an aircraft engine onto reconstituted human bronchial epithelia (HBE) at air-liquid interface under conditions similar to in vivo airways to mimic realistic human exposure. The toxicity of non-volatile PM (nvPM) from a CFM56-7B26 aircraft engine was evaluated under realistic engine conditions by sampling and exposing HBE derived from donors of normal and compromised health status to exhaust for 1 h followed by biomarker analysis 24 h post exposure. Particle deposition varied depending on the engine thrust levels with 85% thrust producing the highest nvPM mass and number emissions with estimated surface deposition of 3.17 × 10

Indexed as

Air PollutantsAir PollutionAircraftHumansParticulate MatterVehicle EmissionsAir PollutantsParticulate MatterVehicle EmissionsAerosolAircraft engine exhaustBronchial epithelial cell cultureCellular responseNon-volatile particulate matter

Identifiers

PMID35623573
PMCPMC10024864
OpenAlexW4281572473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.