Evidence map›Paper›PMID 35623024›Full record

ArticleJCO oncology practice2022

Finding the Lowest-Cost Pharmacy for Cancer Supportive Care Medications: Not So Easy.

Andrew Etteldorf, Shannon Rotolo, Ramy Sedhom, Rachel I Vogel, Anne Blaes, Stacie B Dusetzina, Beth Virnig, Arjun Gupta

Abstract read
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew EtteldorfUniversity of Minnesota, Minneapolis, MN.
Shannon RotoloUniversity of Chicago Medicine, Chicago, IL.ORCID 0000-0003-1577-6656
Ramy SedhomUniversity of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-8937-0726
Rachel I VogelUniversity of Minnesota, Minneapolis, MN.ORCID 0000-0003-0149-8464
Anne BlaesUniversity of Minnesota, Minneapolis, MN.ORCID 0000-0002-5433-4810
Stacie B DusetzinaVanderbilt University, Nashville, TN.ORCID 0000-0002-3907-9196
Beth VirnigUniversity of Minnesota, Minneapolis, MN.ORCID 0000-0002-8153-7488
Arjun GuptaUniversity of Minnesota, Minneapolis, MN.ORCID 0000-0003-0875-4731

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
NCI NIH HHS P30 CA077598
6 · The paper itself

Abstract

purposeTo decrease the financial burden on people with cancer, clinicians and patients increasingly use medication price comparison websites to seek pharmacies where medications may be cheaper. Shopping around at different pharmacies can add additional time and logistic burden to patients and care partners. We sought to determine whether a single pharmacy consistently offered the lowest price for symptom control medications.

methodsWe compiled medications/formulations used to manage two common cancer-associated symptoms: nausea/vomiting and anorexia/cachexia. We extracted discounted, lowest price with coupon prices for a typical fill of these medications at nine pharmacies in Minneapolis, MN, using GoodRx. We compared prices across formulations and pharmacies to assess whether a pharmacy consistently offered the lowest price.

resultsWe included 24 formulations for nausea/vomiting (14 generic and 10 brand-name) and 19 for anorexia/cachexia (12 generic and seven brand-name). Prices for brand-name formulations were similar across pharmacies, but prices of generic formulations varied widely across pharmacies. For example, the prices of a seven-unit fill of generic 5-mg olanzapine tablets ranged from $4 to $57 US dollars. No single pharmacy consistently offered the lowest price across the formulations studied. For example, for the 12 generic formulations for anorexia/cachexia, one pharmacy had the highest price for four formulations and the lowest price for two others.

conclusionIn this study of discounted medication prices, we found that no single pharmacy in an urban zip code consistently offered the lowest price for medications used to manage two common cancer-associated symptoms. Well-intentioned efforts to pursue the cheapest source of each medication by visiting multiple pharmacies may add extra time and logistic toxicity to patients and care partners. This approach can increase redundant scripts and expose patients to medication-related adverse events.

Indexed as

NeoplasmsPharmaciesPharmacyAnorexiaCachexiaDrugs, GenericHumansNauseaVomitingDrugs, Generic

Identifiers

PMID35623024
PMCPMC9377721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.