ArticleJCO global oncology2022
Colorectal Cancer Treatment Characteristics and Concordance With Guidelines in Sri Lanka: Results From a Hospital-Based Cancer Registry.
Article in JCO global oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Awareness of colorectal cancer symptoms and risk factors: a cross-sectional study at the largest tertiary care centre in Sri Lanka.BMJ open · 2025Article
- A Report from a Community-Centric Cancer Control Approach in the Post-Conflict Northern Province of Sri Lanka.International journal of environmental research and public health · 2025Article
- Metagenomic analysis of colonic tissue and stool microbiome in patients with colorectal cancer in a South Asian population.BMC cancer · 2024Article
- Guideline- Versus Non-Guideline-Based Neoadjuvant Management of Clinical T4 Rectal Cancer.Current oncology (Toronto, Ont.) · 2023Article
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10 authors.
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Abstract
purposeColorectal cancer (CRC) ranks among the top five incident cancers in Sri Lanka (SL). Here, we describe disease characteristics and treatment patterns of patients with CRC in SL.
methodsAll adult patients (age > 18 years) diagnosed with CRC during 2016-2020 were identified from the National Cancer Institute SL cancer registry. Cancer stage at diagnosis was defined according to the seventh edition of the TNM staging system. Concordance between recommendations for adjuvant therapy and actual rates of delivery was also analyzed. Descriptive statistics were used to describe the study cohort and treatment patterns.
resultsA total of 1,578 patients were diagnosed with CRC during the study period, 53% (n = 830) with colon cancer and 47% (n = 748) with rectal cancer. Mean age was 61 (range, 18-91) years. Stage distribution was 13%, 28%, 46%, and 12% for stage I, II, III, and IV cancers, respectively. Adjuvant chemotherapy was delivered to 82% of patients with stage III colon cancer. There was a lack of concordance with delivery of neoadjuvant chemoradiotherapy, which was only delivered to 50% of patients with stage III rectal cancer for whom this treatment was indicated.
conclusionAging population and advanced stage of CRC at diagnosis will continue to challenge the provision of high-quality CRC care in SL. Further quantitative and qualitative research may help better understand the nonconcordance with treatment guidelines. Such information would help ease the burden of advanced-stage CRC in SL.
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