Evidence map›Paper›PMID 35622911›Full record

ArticleScience advances2022

Light-induced protein structural dynamics in bacteriophytochrome revealed by time-resolved x-ray solution scattering.

Sang Jin Lee, Tae Wu Kim, Jong Goo Kim, Cheolhee Yang, So Ri Yun, Changin Kim, Zhong Ren, Indika Kumarapperuma, Jane Kuk, Keith Moffat and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sang Jin LeeDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0002-1302-0241
Tae Wu KimDepartment of Chemistry, Mokpo National University, Muan-gun, Jeollanam-do, 58554, Republic of Korea.ORCID 0000-0002-6370-0907
Jong Goo KimDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0002-9267-7697
Cheolhee YangDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0002-4472-9982
So Ri YunDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0002-6653-1803
Changin KimDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0002-6248-6101
Zhong RenDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0001-7098-3127
Indika KumarapperumaDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-2097-3734
Jane KukDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8886-4078
Keith MoffatDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.
Xiaojing YangDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-1394-9189
Hyotcherl IheeDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.ORCID 0000-0001-9051-9946
Korea Advanced Institute of Science and Technology · KRUniversity of Illinois Chicago · USUniversity of Chicago · USMokpo National University · KR

Funding

Electric Field-stimulated Protein MechanicsP41GM118217 · NIGMS · UNIVERSITY OF CHICAGO · PI RANGANATHAN, RAMA · 2019 to 2021
$5.3M
TIME-RESOLVED MACROMOLECULAR CRYSTALLOGRAPHYR01GM036452 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 1986 to 2012
$4.7M
Structures, Dynamics and Signaling Mechanisms of Modular PhotoreceptorsR01EY024363 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YANG, XIAOJING · 2014 to 2021
$2.9M
BioCARS: A Synchrotron Structure Biology ResourceR24GM111072 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 2013 to 2016
$2.3M
TIME-RESOLVED MACROMOLECULAR CRYSTALLOGRAPHYR37GM036452 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 1995 to 2004
$1.9M
NEI NIH HHS R01 EY024363NIGMS NIH HHS P41 GM118217NIGMS NIH HHS R01 GM036452NIGMS NIH HHS R24 GM111072NIGMS NIH HHS R37 GM036452
6 · The paper itself

Abstract

Bacteriophytochromes (BphPs) are photoreceptors that regulate a wide range of biological mechanisms via red light-absorbing (Pr)-to-far-red light-absorbing (Pfr) reversible photoconversion. The structural dynamics underlying Pfr-to-Pr photoconversion in a liquid solution phase are not well understood. We used time-resolved x-ray solution scattering (TRXSS) to capture light-induced structural transitions in the bathy BphP photosensory module of

Identifiers

PMID35622911
PMCPMC9140987
OpenAlexW4281994635

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.