Evidence map›Paper›PMID 35622902›Full record

ArticleScience immunology2022

Persistent CAD activity in memory CD8

Michael D Claiborne, Srona Sengupta, Liang Zhao, Matthew L Arwood, Im-Meng Sun, Jiayu Wen, Elizabeth A Thompson, Marisa Mitchell-Flack, Marikki Laiho, Jonathan D Powell

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michael D ClaiborneBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-7633-0159
Srona SenguptaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-8426-4905
Liang ZhaoBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-2126-6778
Matthew L ArwoodBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-4737-9786
Im-Meng SunBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Jiayu WenBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Elizabeth A ThompsonBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0001-8464-9904
Marisa Mitchell-FlackBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-3192-0865
Marikki LaihoDepartment of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Jonathan D PowellBloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-0850-2852
Bloomberg (United States) · USJohns Hopkins University · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI WILLIAM George NELSON · 1985 to 2026
$208.6M
Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
A central role for mTOR in Determining T Cell Activation versus ToleranceR01AI077610 · NIAID · JOHNS HOPKINS UNIVERSITY · PI POWELL, JONATHAN D · 2009 to 2019
$4.0M
Mechanistic analyses of a novel RNA polymerase I transcription checkpointR01GM121404 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI LAIHO, MARIKKI, SCHNEIDER, DAVID ALAN · 2017 to 2020
$2.0M
NCI NIH HHS P30 CA006973NIAID NIH HHS R01 AI077610NIGMS NIH HHS R01 GM121404NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

Memory CD8

Indexed as

Aspartate CarbamoyltransferaseCarbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)CD8-Positive T-LymphocytesCytokinesPyrimidinesAspartate CarbamoyltransferaseCarbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)CytokinesPyrimidines

Identifiers

PMID35622902
PMCPMC9307092
OpenAlexW4281891818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.