Evidence map›Paper›PMID 35622702›Full record

ArticleTropical medicine and infectious disease2022

Antimicrobial Prescribing Patterns in Patients with COVID-19 in Russian Multi-Field Hospitals in 2021: Results of the Global-PPS Project.

Sergey Avdeev, Svetlana Rachina, Yuliya Belkova, Roman Kozlov, Ann Versporten, Ines Pauwels, Herman Goossens, Elena Bochanova, Elena Elokhina, Ulyana Portnjagina and 4 more

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sergey AvdeevFirst Moscow State Medical University, 119435 Moscow, Russia.ORCID 0000-0002-5999-2150
Svetlana RachinaFirst Moscow State Medical University, 119435 Moscow, Russia.ORCID 0000-0002-3329-7846
Yuliya BelkovaSmolensk State Medical University, 214019 Smolensk, Russia.ORCID 0000-0002-4422-6517
Roman KozlovSmolensk State Medical University, 214019 Smolensk, Russia.
Ann VersportenVaccine and Infectious Disease Institute, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0002-3551-6643
Ines PauwelsVaccine and Infectious Disease Institute, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-0106-2118
Herman GoossensVaccine and Infectious Disease Institute, University of Antwerp, 2610 Antwerp, Belgium.
Elena BochanovaKrasnoyarsk State Medical University n.a. Professor V. F. Voyno-Yasenetsky, 660022 Krasnoyarsk, Russia.
Elena ElokhinaOmsk Regional Clinical Hospital, 644111 Omsk, Russia.
Ulyana PortnjaginaNorth-Eastern Federal University, 677007 Yakutsk, Russia.
Olga ReshetkoSaratov State Medical University n.a. V. I. Razumovsky, 410000 Saratov, Russia.
Igor SychevCity Clinical Hospital n.a. S.S. Yudin, 117198 Moscow, Russia.
Darya StrelkovaFirst Moscow State Medical University, 119435 Moscow, Russia.ORCID 0000-0002-2124-0623
On Behalf Of Russian Global-Pps Project Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic is a global public health challenge with understudied effects on antimicrobial usage. We aimed to analyze antimicrobial prescribing patterns in COVID-19 patients in Russian multi-field hospitals by means of the Global-PPS Project developed by the University of Antwerp. Out of 999 patients in COVID-19 wards in six hospitals surveyed in 2021, 51.3% received antimicrobials (79% in intensive care, 47.5% in medical wards). Systemic antivirals and antibiotics were prescribed to 31% and 35.1% of patients, respectively, and a combination of both to 14.1% of patients. The top antivirals administered were favipiravir (65%), remdesivir (19.2%), and umifenovir (15.8%); the top antibiotics were ceftriaxone (29.7%), levofloxacin (18%), and cefoperazone/sulbactam (10.4%). The vast majority of antibiotics was prescribed for treatment of pneumonia or COVID-19 infection (59.3% and 25.1%, respectively). Treatment was based on biomarker data in 42.7% of patients but was targeted only in 29.6% (6.7% for antibiotics). The rate of non-compliance with guidelines reached 16.6%. Antimicrobial prescribing patterns varied considerably in COVID-19 wards in Russian hospitals with groundlessly high rates of systemic antibiotics. Antimicrobial usage surveillance and stewardship should be applied to inpatient care during the COVID-19 pandemic.

Indexed as

antimicrobialsCOVID-19hospitalpoint prevalence survey

Identifiers

PMID35622702
PMCPMC9147532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.