Evidence map›Paper›PMID 35622605›Full record

ArticleToxins2022

Genotoxicity of Natural Water during the Mass Development of Cyanobacteria Evaluated by the Allium Test Method: A Model Experiment with Microcosms.

Dmitry S Pesnya, Svetlana A Kurbatova, Andrey N Sharov, Ekaterina N Chernova, Igor Y Yershov, Galina V Shurganova, Ekaterina L Vodeneeva

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dmitry S PesnyaLaboratory of Water Ecosystems, Department of Ecology, Institute of Biology and Biomedicine, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.ORCID 0000-0001-9741-1313
Svetlana A KurbatovaLaboratory of Water Ecosystems, Department of Ecology, Institute of Biology and Biomedicine, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.
Andrey N SharovLaboratory of Algology, Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, 152742 Borok, Russia.ORCID 0000-0001-7581-2538
Ekaterina N ChernovaLaboratory of Eco-Chemical Studies, St. Petersburg Federal Research Center of the Russian Academy of Sciences (SPC RAS), Scientific Research Centre for Ecological Safety of the Russian Academy of Sciences, 197110 St. Petersburg, Russia.ORCID 0000-0002-2135-4540
Igor Y YershovLaboratory of Water Ecosystems, Department of Ecology, Institute of Biology and Biomedicine, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.
Galina V ShurganovaLaboratory of Water Ecosystems, Department of Ecology, Institute of Biology and Biomedicine, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.
Ekaterina L VodeneevaLaboratory of Water Ecosystems, Department of Ecology, Institute of Biology and Biomedicine, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.
Institute of Biology of Inland Waters named Ivan Dmitrievich Papanin · RUN. I. Lobachevsky State University of Nizhny Novgorod · RURussian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanobacteria, which develop abundantly in aquatic ecosystems, can be harmful to humans and animals not only by releasing toxins that cause poisoning but also by provoking cytogenetic effects. The influence of the mass development of cyanobacteria on the genotoxic properties of natural water has been studied in model ecosystems (microcosms) with different compositions of biotic components (zooplankton, amphipods and fish). The validated plant test system "Allium test" was used in this study. Genotoxic effects were detected at microcystin concentrations below those established by the World Health Organization (WHO) for drinking water. In all experimental treatments, cells with disorders such as polyploidy and mitotic abnormalities associated with damage to the mitotic spindle, including c-mitosis, as well as lagging chromosomes were found. Genotoxic effects were associated with the abundance of cyanobacteria, which, in turn, depended on the composition of aquatic organisms in the experimental ecosystem. Fish, to a greater extent than other aquatic animals, maintain an abundance of cyanobacteria. After one month, in microcosms with fish, mitotic abnormalities and polyploidy continued to be detected, whereas in other treatments, there were no statistically significant genotoxic effects. In microcosms with amphipods, the number and biomass of cyanobacteria decreased to the greatest extent, and only one parameter of genotoxic activity (frequency of polyploidy) significantly differed from the control.

Indexed as

AlliumCyanobacteriaAnimalsDNA DamageEcosystemPolyploidyWaterWaterAllium testcyanobacteriacyanotoxinsgenotoxicityharmful cyanobacterial bloomsmicrocosmsmicrocystins

Identifiers

PMID35622605
PMCPMC9145725
OpenAlexW4281253154

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.