Evidence map›Paper›PMID 35622591›Full record

ReviewToxins2022

Biological Effects of Animal Venoms on the Human Immune System.

Zharick Avalo, María Claudia Barrera, Manuela Agudelo-Delgado, Gabriel J Tobón, Carlos A Cañas

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Brief history of ophidiology and ophidism in Colombia.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026
    Review
  2. Article
  3. Article
  4. Unveiling the therapeutic journey of snail mucus in diabetic wound care.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zharick AvaloEscuela de Bacteriología, Facultad de Salud, Universidad del Valle, Cali 76001, Colombia.
María Claudia BarreraDepartment de Microbiología, Universidad del Valle, Cali 76001, Colombia.
Manuela Agudelo-DelgadoEscuela de Bacteriología, Facultad de Salud, Universidad del Valle, Cali 76001, Colombia.ORCID 0000-0002-3831-7930
Gabriel J TobónDepartment of Medical Microbiology, Southern Illinois University School of Medicine, Springfield, IL 62901, USA.
Carlos A CañasUnidad de Reumatología, Fundación Valle del Lili, Cali 760032, Colombia.
Universidad del Valle · COFundación Valle del Lili · COSouthern Illinois University School of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venoms are products of specialized glands and serve many living organisms to immobilize and kill prey, start digestive processes and act as a defense mechanism. Venoms affect different cells, cellular structures and tissues, such as skin, nervous, hematological, digestive, excretory and immune systems, as well as the heart, among other structures. Components of both the innate and adaptive immune systems can be stimulated or suppressed. Studying the effects on the cells and molecules produced by the immune system has been useful in many biomedical fields. The effects of venoms can be the basis for research and development of therapeutic protocols useful in the modulation of the immunological system, including different autoimmune diseases. This review focuses on the understanding of biological effects of diverse venom on the human immune system and how some of their components can be useful for the study and development of immunomodulatory drugs.

Indexed as

Autoimmune DiseasesBody FluidsAnimalsDigestionHumansImmune SystemVenomsVenomsadaptive immune systemenvenomationimmunomodulatoryimmunosuppressioninnate immune system

Identifiers

PMID35622591
PMCPMC9143185
OpenAlexW4280573571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.