Evidence map›Paper›PMID 35622566›Full record

ArticleToxins2022

Probing the Mechanism of Action of Cry41Aa on HepG2 through the Establishment of a Resistant Subline.

Wided Souissi, Tweedie Alistair, Barbara Domanska, Eva Fortea, Michelle J West, Jean-Louis Schwartz, Neil Crickmore

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Wided SouissiSchool of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Tweedie AlistairSchool of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Barbara DomanskaSchool of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Eva ForteaDepartement of Pharmacology et Physiology, University of Montreal, Montreal, QC H3C 3J7, Canada.
Michelle J WestSchool of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.ORCID 0000-0002-9497-9365
Jean-Louis SchwartzDepartement of Pharmacology et Physiology, University of Montreal, Montreal, QC H3C 3J7, Canada.
Neil CrickmoreSchool of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.ORCID 0000-0002-8448-0763
University of Sussex · GBUniversité de Montréal · CA

Funding

Medical Research Council MR/S009620/1
6 · The paper itself

Abstract

Cry41Aa, also called parasporin-3, belongs to a group of toxins from the entomopathogenic bacterium

Indexed as

Bacillus thuringiensisBacterial ProteinsHep G2 CellsHL-60 CellsHumansBacterial ProteinsAQP9cry toxinHepG2parasporin

Identifiers

PMID35622566
PMCPMC9147150
OpenAlexW4225396535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.