ArticleAmerican journal of physiology. Heart and circulatory physiology2022
Metabolic signatures of pregnancy-induced cardiac growth.
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In one paragraph
Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
11.0field-weighted citation impact, top 1% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024Guideline
- From bump to pump: extracellular matrix remodeling, dynamics, and biomechanics in the maternal heart.American journal of physiology. Heart and circulatory physiology · 2026Review
- Peripartum-Associated Heart Failure Develops Independently of RHOT Proteins.International journal of molecular sciences · 2026Article
- Pregnancy precipitates metabolic imbalance and accelerates death in an animal model of mitochondrial cardiomyopathy.Molecular metabolism · 2026Article
- When pregnancy tests the heart: voluntary wheel running attenuates HFHS-associated postpartum hemodynamic dysfunction.American journal of physiology. Heart and circulatory physiology · 2026Article
- Review
- Cardiovascular complications of pregnancy.The Journal of clinical investigation · 2026Review
- Immunocytes Play a Crucial Role as Mediators in the Protective Effects of D-β-Hydroxybutyrate Dehydrogenase 1 against Type 2 Diabetes Mellitus: A Mendelian Randomization StudyEndocrine, metabolic & immune disorders drug targets · 2026Article
- Meteorin-like controls metabolic adaptations and physiological myocardial remodeling in pregnancy and lactation.Frontiers in endocrinology · 2026Article
- Calcium Signaling and Cardiac Adaptation to Stress: Focus on Pregnancy and Diabetes.Biomolecules · 2025Review
- Postpartum metabolomics profile predicts 8-years postdelivery women's subclinical atherosclerosis measures.Scientific reports · 2025Article
- Don't go vaping my heart: e-cigarette exposure during pregnancy promotes peripartum ventricular arrhythmias and sympathetic dominance.American journal of physiology. Heart and circulatory physiology · 2025Article
- Aims and Rationale of a National Registry Integrating Clinical, Echocardiographic, and Multi-Omics Profiling to Promote Precision Medicine in Peripartum Cardiomyopathy.Biomedicines · 2025Article
- Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19.Journal of extracellular vesicles · 2025Article
- Maternal cardiovascular research and education should be prioritized in the United States.American journal of physiology. Heart and circulatory physiology · 2025Article
- Gestational arsenite exposure alters maternal postpartum heart size and induces CaAmerican journal of physiology. Heart and circulatory physiology · 2025Article
- Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.Frontiers in cardiovascular medicine · 2025Article
- Machine learning: a new era for cardiovascular pregnancy physiology and cardio-obstetrics research.American journal of physiology. Heart and circulatory physiology · 2024Review
- Cardiac mitochondrial metabolism during pregnancy and the postpartum period.American journal of physiology. Heart and circulatory physiology · 2024Article
- Prenatal arsenite exposure alters maternal cardiac remodeling during late pregnancy.Toxicology and applied pharmacology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 2 countries.
Kyle L FulghumDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Juliette B SmithDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Julia CharikerKentucky INBRE Genomics Core, University of Louisville, Louisville, Kentucky.
Lauren F GarrettDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Kenneth R BrittianDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Pawel K LorkiewiczDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.ORCID 0000-0002-1755-9826
Lindsey A McNallyDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Shizuka UchidaCenter for RNA Medicine, Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.ORCID 0000-0003-4787-8067
Steven P JonesDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.ORCID 0000-0001-5376-8089
Bradford G HillDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.
Helen E CollinsDiabetes and Obesity Center, Christina Lee Brown Envirome Institute, Division of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky.ORCID 0000-0002-9302-6044
University of Louisville · USAalborg University · DK
Funding
WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Bruce A Mattingly · 2012 to 2026
$60.1MSupplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4MTBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY · 2018 to 2022
$6.3MBiosynthetic Pathways in Cardiac RemodelingR01HL147844 · NHLBI · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY, JONES, STEVEN P · 2019 to 2022
$3.0MImaging and Physiology Core: High Frequency, High Resolution Ultrasound Imaging SystemS10OD025178 · OD · UNIVERSITY OF LOUISVILLE · PI JONES, STEVEN P · 2019 to 2019
$364kMetabolic regulation of exercise-induced adaptation in striated muscleF31HL154663 · NHLBI · UNIVERSITY OF LOUISVILLE · PI FULGHUM, KYLE · 2020 to 2022
$86kHHS | National Institutes of Health (NIH) S10OD025178HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL147844HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL154663HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM103436HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM127607NHLBI NIH HHS F31 HL154663NHLBI NIH HHS R01 HL147844NIGMS NIH HHS P20 GM103436NIGMS NIH HHS P30 GM127607NIGMS NIH HHS R24 GM137786NIH HHS S10 OD025178
Abstract
The goal of this study was to develop an atlas of the metabolic, transcriptional, and proteomic changes that occur with pregnancy in the maternal heart. Timed pregnancy studies in FVB/NJ mice revealed a significant increase in heart size by
Indexed as
HeartProteomicsAnimalsCardiomegalyFemaleMiceMitochondria, HeartMyocardiumOxidation-ReductionPregnancyhypertrophymetabolomicspregnancyproteomicstranscriptomics
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.