Evidence map›Paper›PMID 35622504›Full record

ArticleInternational journal of immunopathology and pharmacology

Laboratory biomarker predictors for disease progression and outcome among Egyptian COVID-19 patients.

Lamiaa A Fathalla, Lamyaa M Kamal, Omina Salaheldin, Mahmoud A Khalil, Mahmoud M Kamel, Hagar H Fahim, Youssef As Abdel-Moneim, Jawaher A Abdulhakim, Ahmed S Abdel-Moneim, Yomna M El-Meligui

Open access · goldAbstract read
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Lamiaa A FathallaDepartment of Clinical Pathology, 68804National Cancer Institute, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-2918-9922
Lamyaa M KamalDepartment of Clinical and Chemical pathology, Elsahel Teaching Hospital, MOH, Cairo, Egypt.
Omina SalaheldinDepartment of Clinical Pathology, Ahmed Maher Education Hospital, Cairo, Egypt.
Mahmoud A KhalilDepartment of Tropical Medicine and Infectious disease, Imbaba Fever Hospital, MOH, Cairo, Egypt.
Mahmoud M KamelDepartment of Clinical Pathology, 68804National Cancer Institute, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-0264-3096
Hagar H FahimClinical Pathology Department, Baheya Centre for Early Detection and Treatment of Breast.
Youssef As Abdel-MoneimUndergraduate student, Faculty of Medicine, 158411Beni-Suef University, Beni-Suef, Egypt.
Jawaher A AbdulhakimDepartment of Medical Laboratory, College of Applied Medical Sciences, 435020Taibah University, Yanbu, Saudi Arabia.
Ahmed S Abdel-MoneimMicrobiology Department, College of Medicine, 158409Taif University, Al-Taif, Saudi Arabia.ORCID https://orcid.org/0000-0002-3148-6782
Yomna M El-MeliguiDepartment of Clinical Pathology, 68804National Cancer Institute, Cairo University, Cairo, Egypt.
Cairo University · EGBeni-Suef University · EGResearch Institute of Ophthalmology · EGTaibah University · SATaif University · SAUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic resulted in more than five hundred million infected cases worldwide. The current study aimed to screen the correlation of different laboratory findings with disease severity and clinical outcomes of coronavirus disease (COVID-19) among Egyptian patients to obtain prognostic indicators of disease severity and outcome.A total of 112 laboratory-confirmed COVID-19 patients were examined. According to the severity of the disease, these patients were divided into three main groups: mild, moderate and severe cases. In addition, clinical characteristics and laboratory findings, including Hb, platelet count, white blood cell count, lymphocyte percentage, neutrophil percentage, neutrophil lymphocyte ratio (NLR), D-dimer, highly sensitive C-reactive protein (HS-CRP), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and creatinine, were measured.The presence of hypertension and/or diabetes was found to be a significant risk factor for disease severity and poor outcome. Increased respiratory rate, levels of SpO

Indexed as

COVID-19C-Reactive ProteinBiomarkersDisease ProgressionEgyptHumansL-Lactate DehydrogenaseSARS-CoV-2BiomarkersC-Reactive ProteinL-Lactate DehydrogenaseCOVID-19D-dimerhighly sensitive C-reactive proteinneutrophil lymphocyte ratio and lactate dehydrogenase

Identifiers

PMID35622504
PMCPMC9150244
OpenAlexW4282929422

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.