Evidence map›Paper›PMID 35622095›Full record

ArticleCalcified tissue international2022

Bone Mass Accrual in First Six Months of Life: Impact of Maternal Diabetes, Infant Adiposity, and Cord Blood Adipokines.

Sowmya Krishnan, Christopher E Aston, David A Fields, April M Teague, Timothy J Lyons, Steven D Chernausek

Open access · greenAbstract read
In one paragraph

Article in Calcified tissue international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sowmya KrishnanDepartment of Pediatrics, Section of Diabetes and Endocrinology, University of Oklahoma Health Sciences Center, Harold Hamm Diabetes Center, 1200, Children's avenue Suite 4500, Oklahoma City, OK, 73104, USA. sowmya-krishnan@ouhsc.edu.ORCID 0000-0001-5600-0753
Christopher E AstonDepartment of Pediatrics, Section of Diabetes and Endocrinology, University of Oklahoma Health Sciences Center, Harold Hamm Diabetes Center, 1200, Children's avenue Suite 4500, Oklahoma City, OK, 73104, USA.
David A FieldsDepartment of Pediatrics, Section of Diabetes and Endocrinology, University of Oklahoma Health Sciences Center, Harold Hamm Diabetes Center, 1200, Children's avenue Suite 4500, Oklahoma City, OK, 73104, USA.
April M TeagueHarold Hamm Diabetes Center, Oklahoma City, OK, USA.
Timothy J LyonsDivision of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, Charleston, SC, USA.
Steven D ChernausekDepartment of Pediatrics, Section of Diabetes and Endocrinology, University of Oklahoma Health Sciences Center, Harold Hamm Diabetes Center, 1200, Children's avenue Suite 4500, Oklahoma City, OK, 73104, USA.
University of Oklahoma Health Sciences Center · USMedical University of South Carolina · US

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Janis E Campbell · 2013 to 2026
$68.2M
TRAINING COREP20MD000528 · NIMHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI COPELAND, KENNETH C · 2003 to 2016
$17.8M
Prenatal Conditions and the Pathway to Obesity and Diabetes in ChildrenR01DK089034 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CHERNAUSEK, STEVEN D · 2010 to 2014
$1.4M
NIDDK NIH HHS R01 DK089034NIGMS NIH HHS U54 GM104938NIMHD NIH HHS P20 MD000528
6 · The paper itself

Abstract

The perinatal period is a time of substantial bone mass accrual with many factors affecting long-term bone mineralization. Currently it is unclear what effect maternal gestational/type 2 diabetes has on infant bone mass accrual. This is a prospective study of offspring of Native American and Hispanic mothers with normoglycemia (n = 94) and gestational diabetes or type 2 diabetes (n = 64). Infant anthropometrics were measured at birth, 1, and 6 months of age. Cord blood leptin, high-molecular weight adiponectin (HMWA), pigment epithelium-derived factor (PEDF), vascular epithelium growth factor (VEGF), endoglin, and C-peptide were measured by ELISA. Infants had bone mineral density measurement at 1 month or/and 6 months of age using dual-energy x-ray absorptiometry scan. Mothers with diabetes were older (31 ± 6 years vs 25 ± 4 years) and had higher pre-pregnancy BMI (32.6 ± 5.8 vs 27.2 ± 6.4 kg/m

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2AdipokinesAdiposityBone DensityC-PeptideFemaleFetal BloodHumansInfantInfant, NewbornLeptinObesityPregnancyProspective StudiesVascular Endothelial Growth Factor AAdipokinesC-PeptideLeptinVascular Endothelial Growth Factor ABone massBone mineral contentInfants born to diabetes mothersMaternal diabetes

Identifiers

PMID35622095
PMCPMC10085057
OpenAlexW4281787881

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.