Evidence map›Paper›PMID 35621979›Full record

ArticleMarine drugs2022

An Octopus-Derived Peptide with Antidiuretic Activity in Rats.

Ye-Ji Kim, Jei Ha Lee, Seung-Hyun Jung, Ki Hyun Kim, Chang-Hoon Choi, Seonmi Jo, Dong Ho Woo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ye-Ji KimResearch Center for Convergence Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Jei Ha LeeDepartment of Genetic Resources, National Marine Biodiversity Institute of Korea, Seocheon 33662, Korea.
Seung-Hyun JungDepartment of Genetic Resources, National Marine Biodiversity Institute of Korea, Seocheon 33662, Korea.ORCID 0000-0002-9870-0923
Ki Hyun KimDepartment of Genetic Resources, National Marine Biodiversity Institute of Korea, Seocheon 33662, Korea.
Chang-Hoon ChoiResearch Center for Convergence Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Seonmi JoDepartment of Genetic Resources, National Marine Biodiversity Institute of Korea, Seocheon 33662, Korea.ORCID 0000-0002-0305-3250
Dong Ho WooResearch Center for Convergence Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.ORCID 0000-0003-3366-3831
Marine Biodiversity Institute of Korea · KRKorea Institute of Toxicology · KR

Funding

grants from the Collaborative Genome Program of the Korea Institute of Marine Science and Technology Promotion (KIMST) funded by the Ministry of Oceans and Fisheries (MOF) 20180430 to DHWgrants from the National Marine Biodiversity Institute (MABIK) Research Program 2022M00400 to SJthe Ministry of Food and Drug Safety 20182MFDS423
6 · The paper itself

Abstract

Discovering new drug candidates with high efficacy and few side effects is a major challenge in new drug development. The two evolutionarily related peptides oxytocin (OXT) and arginine vasopressin (AVP) are known to be associated with a variety of physiological and psychological processes via the association of OXT with three types of AVP receptors. Over decades, many synthetic analogs of these peptides have been designed and tested for therapeutic applications; however, only a few studies of their natural analogs have been performed. In this study, we investigated the bioactivity and usefulness of two natural OXT/AVP analogs that originate from the marine invertebrate

Indexed as

Antidiuretic AgentsOctopodiformesOxytocinAnimalsArginine VasopressinDeamino Arginine VasopressinFelypressinRatsRats, Sprague-DawleyReceptors, VasopressinAntidiuretic AgentsArginine VasopressinDeamino Arginine VasopressinFelypressinOxytocinReceptors, Vasopressinantidiureticcephalotocinoctopressinoctopusvasopressin

Identifiers

PMID35621979
PMCPMC9144402
OpenAlexW4280525825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.