Evidence map›Paper›PMID 35621967›Full record

ArticleMarine drugs2022

Inhibition of Lipopolysaccharide-Induced Inflammatory Signaling by Soft Coral-Derived Prostaglandin A

Osamu Ohno, Eika Mizuno, Junichiro Miyamoto, Tomoyuki Hoshina, Takuya Sano, Kenji Matsuno

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Osamu OhnoDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.ORCID 0000-0002-8147-6857
Eika MizunoDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.
Junichiro MiyamotoDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.
Tomoyuki HoshinaDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.
Takuya SanoDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.
Kenji MatsunoDepartment of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano, Tokyo 192-0015, Japan.
Kogakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria and causes inflammatory diseases. We searched MeOH extracts of collected marine organisms for inhibitors of LPS-induced nitric oxide (NO) production in RAW264.7 cells and identified prostaglandin A

Indexed as

AnthozoaLipopolysaccharidesAnimalsMacrophagesMiceNF-kappa BNitric OxideLipopolysaccharidesNF-kappa BNitric OxideLPSPGA2RAW264.7soft coral

Identifiers

PMID35621967
PMCPMC9143063
OpenAlexW4229452798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.