Evidence map›Paper›PMID 35621928›Full record

ArticleMarine drugs2022

Lulworthinone: In Vitro Mode of Action Investigation of an Antibacterial Dimeric Naphthopyrone Isolated from a Marine Fungus.

Eric Juskewitz, Ekaterina Mishchenko, Vishesh K Dubey, Marte Jenssen, Martin Jakubec, Philip Rainsford, Johan Isaksson, Jeanette H Andersen, Johanna U Ericson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Eric JuskewitzResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0002-0769-5621
Ekaterina MishchenkoResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019 Tromsø, Norway.
Vishesh K DubeyResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0002-2753-0445
Marte JenssenMarbio, The Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0001-7563-0005
Martin JakubecDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0002-6180-6900
Philip RainsfordDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019 Tromsø, Norway.
Johan IsakssonDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0001-6287-7594
Jeanette H AndersenMarbio, The Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0002-6059-060X
Johanna U EricsonResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019 Tromsø, Norway.ORCID 0000-0001-5196-4932
UiT The Arctic University of Norway · NO

Funding

The Research Council of Norway 269425
6 · The paper itself

Abstract

Treatment options for infections caused by antimicrobial-resistant bacteria are rendered ineffective, and drug alternatives are needed-either from new chemical classes or drugs with new modes of action. Historically, natural products have been important contributors to drug discovery. In a recent study, the dimeric naphthopyrone lulworthinone produced by an obligate marine fungus in the family

Indexed as

Methicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsBacteriaFungiGram-Positive BacteriaMicrobial Sensitivity TestsPolymersAnti-Bacterial AgentsPolymersantimicrobial agentsB. subtiliscolloidal aggregateFtsZmarine natural productmode of actionMRSA

Identifiers

PMID35621928
PMCPMC9147123
OpenAlexW4224312266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.