Evidence map›Paper›PMID 35621873›Full record

ReviewJournal of cardiovascular development and disease2022

Is Obesity a Risk Factor for Carotid Atherosclerotic Disease?-Opportunistic Review.

Joana Ferreira, Pedro Cunha, Alexandre Carneiro, Isabel Vila, Cristina Cunha, Cristina Silva, Adhemar Longatto-Filho, Amílcar Mesquita, Jorge Cotter, Margarida Correia-Neves and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Joana FerreiraVascular Surgery Department, Hospital de Trás-os-Montes, 5000-508 Vila Real, Portugal.ORCID 0000-0001-6761-4881
Pedro CunhaLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-8518-4130
Alexandre CarneiroRadiology Department, Unidade Local de Saúde Alto Minho, 4904-858 Viana do Castelo, Portugal.
Isabel VilaLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Cristina CunhaLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Cristina SilvaLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Adhemar Longatto-FilhoLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-5779-9752
Amílcar MesquitaVascular Surgery Department, Hospital da Senhora da Oliveira, 4835-044 Guimarães, Portugal.
Jorge CotterLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Margarida Correia-NevesLife and Health Science Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
Armando MansilhaFaculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal.
Hospital da Senhora da Oliveira Guimarães · PTAdministração Regional de Saúde de Lisboa e Vale do Tejo · PTUniversidade de São Paulo · BRUniversidade do Porto · PTUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a risk factor for coronary atherosclerosis. However, the influence of adipose tissue in carotid atherosclerosis is not completely understood. No systematic review/meta-analysis was previously performed to understand if obesity is a risk factor for carotid atherosclerosis. This paper aims to provide an opportunistic review of the association between obesity and carotid atherosclerosis and define the role of the different adipose tissue depots in the characteristics of carotid stenosis. The databases PubMed and Cochrane Library were searched on 15-27 April and 19 May 2021. A total of 1750 articles published between 1985 and 2019 were identified, 64 were preselected, and 38 papers (35,339 subjects) were included in the final review. The most frequent methods used to determine obesity were anthropometric measures. Carotid plaque was mostly characterized by ultrasound. Overall obesity and visceral fat were not associated with the presence of carotid plaque when evaluated separately. Waist-hip ratio, however, was a significant anthropometric measure associated with the prevalence of carotid plaques. As it reflected the ratio of visceral and subcutaneous adipose tissue, the balance between these depots could impact the prevalence of carotid plaques.

Indexed as

carotid atherosclerotic diseaseobesitysubcutaneous adipose tissuevisceral adipose tissue

Identifiers

PMID35621873
PMCPMC9144226
OpenAlexW4280584899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.