Evidence map›Paper›PMID 35621824›Full record

ArticleInsects2022

Meta-Analysis of Immune Induced Gene Expression Changes in Diverse

Ashley L Waring, Joshua Hill, Brooke M Allen, Nicholas M Bretz, Nguyen Le, Pooja Kr, Dakota Fuss, Nathan T Mortimer

Open access · goldAbstract read
In one paragraph

Article in Insects, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. ThebioRxiv : the preprint server for biology · 2025
    Article
  4. Cell-death induced immune response and coagulopathy promote cachexia inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ashley L WaringSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Joshua HillSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Brooke M AllenSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Nicholas M BretzSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Nguyen LeSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.ORCID 0000-0001-7070-9849
Pooja KrSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Dakota FussSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Nathan T MortimerSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.ORCID 0000-0003-3787-9445
Illinois State University · US

Funding

Regulation of Host Signaling by Parasitoid Venom ProteinsR35GM133760 · NIGMS · OREGON STATE UNIVERSITY · PI MORTIMER, NATHAN TERRY · 2019 to 2023
$1.2M
A Novel Drosophila Model to Understand the Role of Innate Immunity in Alzheimer's DiseaseR03AG063314 · NIA · ILLINOIS STATE UNIVERSITY · PI MORTIMER, NATHAN TERRY · 2019 to 2020
$293k
National Institute of Health R35GM133760NIA NIH HHS R03 AG063314NIGMS NIH HHS R35 GM133760
6 · The paper itself

Abstract

Organisms are commonly infected by a diverse array of pathogens and mount functionally distinct responses to each of these varied immune challenges. Host immune responses are characterized by the induction of gene expression, however, the extent to which expression changes are shared among responses to distinct pathogens is largely unknown. To examine this, we performed meta-analysis of gene expression data collected from

Indexed as

Drosophila melanogastergene expressioninnate immunitypathogen infectiontranscriptome analysis

Identifiers

PMID35621824
PMCPMC9147463
OpenAlexW4281390310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.