ReviewCurrent oncology (Toronto, Ont.)2022
The Impact of Dense Breasts on the Stage of Breast Cancer at Diagnosis: A Review and Options for Supplemental Screening.
Review in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Supplemental Screening as an Adjunct to Mammography for Breast Cancer Screening in People With Dense Breasts: A Health Technology Assessment.Ontario health technology assessment series · 2023Pooled it
- Ten Years of Artificial Intelligence in Screening Mammography: A Systematic Review and Meta-Analysis of Diagnostic Accuracy and Clinical Implementation (Literature Published 2015-2025).Diagnostics (Basel, Switzerland) · 2026Review
- Automated Breast Ultrasound in Dense-Breast Screening: Beyond Additional Cancer Detection.Korean journal of radiology · 2026Article
- Emerging miRNA biomarkers in breast cancer: The role of miR-223, miR-326, and miR-429 in tumor profiling.Molecular biology reports · 2026Article
- Evaluation of the diagnostic accuracy of mammography and ultrasonography for breast cancer diagnosis using histopathology as the reference standard: a cross-sectional study.Annals of medicine and surgery (2012) · 2026Article
- Association of Breast Density with Breast Cancer Risk and Stage at Diagnosis: A Korean Nationwide Cohort Study.Cancers · 2025Article
- Article
- Breast density classification using frequency-based features in microwave imaging.Scientific reports · 2025Article
- Collagen architecture in triple negative breast cancer.PloS one · 2025Article
- Performance Metrics of Mammography Screening Programmes in Primary Health Care Centres in Bahrain.International journal of women's health · 2025Article
- Article
- Review
- Artificial intelligence for cancer screening and surveillance.ESMO real world data and digital oncology · 2024Review
- Role of Radiology in the Diagnosis and Treatment of Breast Cancer in Women: A Comprehensive Review.Cureus · 2024Review
- Surgical and Radiology Trainees' Proficiency in Reading Mammograms: the Importance of Education for Cancer Localisation.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024Article
- Stage Shifting by Modifying the Determinants of Breast Cancer Stage at Diagnosis: A Simulation Study.Cancers · 2024Article
- Polygenic risk score-based prediction of breast cancer risk in Taiwanese women with dense breast using a retrospective cohort study.Scientific reports · 2024Article
- Review
- Comparative Analysis of Data Preprocessing Methods in Machine Learning for Breast Cancer Classification.Proceedings. International Conference on Advanced Information Networking and Applications · 2024Article
- Mammographic assessment of breast density as a tool for predicting the response to neoadjuvant therapy in breast cancer patients.Medicine and pharmacy reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of breast cancer screening is to find cancers early to reduce mortality and to allow successful treatment with less aggressive therapy. Mammography is the gold standard for breast cancer screening. Its efficacy in reducing mortality from breast cancer was proven in randomized controlled trials (RCTs) conducted from the early 1960s to the mid 1990s. Panels that recommend breast cancer screening guidelines have traditionally relied on the old RCTs, which did not include considerations of breast density, race/ethnicity, current hormone therapy, and other risk factors. Women do not all benefit equally from mammography. Mortality reduction is significantly lower in women with dense breasts because normal dense tissue can mask cancers on mammograms. Moreover, women with dense breasts are known to be at increased risk. To provide equity, breast cancer screening guidelines should be created with the goal of maximizing mortality reduction and allowing less aggressive therapy, which may include decreasing the interval between screening mammograms and recommending consideration of supplemental screening for women with dense breasts. This review will address the issue of dense breasts and the impact on the stage of breast cancer at the time of diagnosis, and discuss options for supplemental screening.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.