Evidence map›Paper›PMID 35621674›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Outcomes of Intercalary Endoprostheses as a Treatment for Metastases in the Femoral and Humeral Diaphysis.

Michal Mahdal, Lukáš Pazourek, Vasileios Apostolopoulos, Dagmar Adámková Krákorová, Iva Staniczková Zambo, Tomáš Tomáš

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Intercalary Diaphyseal Endoprosthetic Reconstruction.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Review
  4. Article
  5. Article
  6. Treatment of Bone Metastasis.Current oncology (Toronto, Ont.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Michal MahdalFirst Department of Orthopedic Surgery, St. Anne's University Hospital, 65691 Brno, Czech Republic.ORCID 0000-0002-2136-9136
Lukáš PazourekFirst Department of Orthopedic Surgery, St. Anne's University Hospital, 65691 Brno, Czech Republic.ORCID 0000-0003-1535-1842
Vasileios ApostolopoulosFirst Department of Orthopedic Surgery, St. Anne's University Hospital, 65691 Brno, Czech Republic.ORCID 0000-0001-9719-4769
Dagmar Adámková KrákorováClinic of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, 60200 Brno, Czech Republic.ORCID 0000-0002-8402-2797
Iva Staniczková ZamboFaculty of Medicine, Masaryk University, 60177 Brno, Czech Republic.ORCID 0000-0002-1189-0702
Tomáš TomášFirst Department of Orthopedic Surgery, St. Anne's University Hospital, 65691 Brno, Czech Republic.
Masaryk University · CZMasaryk Memorial Cancer Institute · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate the implant survival, functional score and complications of intercalary endoprostheses implanted for metastatic involvement of the femoral and humeral diaphysis.

methodsThe selected group covered patients with bone metastasis who were surgically treated with an intercalary endoprosthesis between 2012 and 2021. The functional outcome was evaluated with the Musculoskeletal Tumor Society (MSTS) scoring system, and complications were evaluated by using the failure classification for prosthetics designed by Henderson.

resultsThe mean follow-up was 29.8 months. In our group of 25 patients with 27 intercalary endoprostheses (18 femurs, 9 humeri), there were 7 implant-related complications (25.9%), which were more common on the humerus (4 cases, 44.4%) than on the femur (3 cases, 16.7%). Only type II failure-aseptic loosening (5 cases, 18.5%)-and type III failure-structural failure (2 cases, 7.4%)-occurred. There was a significantly higher risk of aseptic loosening of the endoprosthesis in the humerus compared with that in the femur (odds ratio 13.79, 95% confidence interval 1.22-151.05,

conclusionsThe resection of bone metastases and replacement with intercalary endoprosthesis has excellent immediate functional results with an acceptable level of complications in prognostically favourable patients.

Indexed as

Bone NeoplasmsFemoral NeoplasmsDiaphysesFemurHumansHumerusPostoperative ComplicationsProstheses and Implantsbone neoplasmdiaphysis of long bonesintercalary endoprosthesismetastasis

Identifiers

PMID35621674
PMCPMC9139707
OpenAlexW4280610456

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.