Evidence map›Paper›PMID 35621646›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Early-Age-Onset Colorectal Cancer in Canada: Evidence, Issues and Calls to Action.

Mary A De Vera, Sharlene Gill, Shady Ashamalla, Dan Schiller, Darren R Brenner, Clarence Wong, Petra Wildgoose, Mary Jane Esplen, Christopher Lieu, Roslyn Fitzpatrick and 2 more

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Direct Medical Spending on Young and Average-Age Onset Colorectal Cancer before and after Diagnosis: a Population-Based Costing Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Mary A De VeraFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0002-2205-2683
Sharlene GillDivision of Medical Oncology, BC Cancer, University of British Columbia, Vancouver, BC V5Z 4E6, Canada.ORCID 0000-0003-3306-3617
Shady AshamallaDepartment of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Dan SchillerDepartment of Surgery, University of Alberta, Edmonton, AB T5H 3V9, Canada.
Darren R BrennerDepartment of Community Health Sciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Clarence WongDivision of Gastroenterology, University of Alberta, Edmonton, AB T6G 2X8, Canada.ORCID 0000-0003-3191-3294
Petra WildgooseSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Mary Jane EsplenDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1P5, Canada.ORCID 0000-0002-6034-2235
Christopher LieuDivision of Medical Oncology, Gastrointestinal Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Roslyn FitzpatrickPatient Advocate, Thornhill, ON L3T 3H1, Canada.
Dylan E O'SullivanDepartment of Community Health Sciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Filomena Servidio-ItalianoColorectal Cancer Resource & Action Network, 700-2 Bloor Street West, Toronto, ON M4W 3E2, Canada.
Alberta Health Services · CASunnybrook Health Science Centre · CAUniversity of Alberta · CAUniversity of British Columbia · CAThornhill Medical (Canada) · CAUniversity of Colorado Anschutz Medical Campus · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inaugural Early-Age-Onset Colorectal Cancer Symposium was convened in June 2021 to discuss the implications of rapidly rising rates of early-age-onset colorectal cancer (EAO-CRC) in Canadians under the age of 50 and the impactful outcomes associated with this disease. While the incidence of CRC is declining in people over the age of 50 in Canada and other developed countries worldwide, it is significantly rising in younger people. Canadians born after 1980 are 2 to 2.5 times more likely to be diagnosed with CRC before the age of 50 than previous generations at the same age. While the etiology of EAO-CRC is largely unknown, its characteristics differ in many key ways from CRC diagnosed in older people and warrant a specific approach to risk factor identification, early detection and treatment. Participants of the symposium offered directions for research and clinical practice, and developed actionable recommendations to address the unique needs of these individuals diagnosed with EAO-CRC. Calls for action emerging from the symposium included: increased awareness of EAO-CRC among public and primary care practitioners; promotion of early detection programs in younger populations; and the continuation of research to identify unique risk factor profiles, tumour characteristics and treatment models that can inform tailored approaches to the management of EAO-CRC.

Indexed as

Colorectal NeoplasmsAgedCanadaHumansIncidenceRisk Factorscolorectal cancerEAO-CRCearly-age-onset colorectal cancerEO-CRC

Identifiers

PMID35621646
PMCPMC9140191
OpenAlexW4229030236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.