ArticleCurrent oncology (Toronto, Ont.)2022
Health Literacy and Clinical Trial Participation in French Cancer Patients: A National Survey.
Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- Improving cancer clinical trial enrollment and patient understanding using TrialTalk, a structured communication method: a pilot randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- How equity in cancer services has been defined and measured, and why it matters: a scoping review of Universal Health Coverage systems.Global health action · 2026Article
- Social Determinants of Health in Metastatic Breast Cancer Care: A Podcast Exploring Challenges and Opportunities in the United States and Canada.Oncology and therapy · 2026Article
- Tackling healthcare providers bias: a systematic review of interventions with implications for inclusive clinical research.EClinicalMedicine · 2025Article
- Enhancing accessibility and impact of digitally enabled clinical trials: the WeShare engagement and equity toolkit.ESMO real world data and digital oncology · 2025Review
- Factors associated with participation in a proton therapy clinical trial: a cross-sectional survey of Danish patients with head and neck cancer.Acta oncologica (Stockholm, Sweden) · 2025Article
- Article
- National Estimates of the Participation of Patients With Cancer in Clinical Research Studies Based on Commission on Cancer Accreditation Data.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Article
- An effort to improve the collection of patient-generated data: readability and understandability of patient-reported outcomes measures in a survivorship cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Exploring patient-reported barriers to participating in proton therapy clinical trials.Technical innovations & patient support in radiation oncology · 2024Article
- Disentangling the reasons why older adults do not readily participate in cancer trials: a socio-epidemiological mixed methods approach.Age and ageing · 2024Article
- Combined Results of Two Cross-Sectional Surveys on the Participation in Clinical Trials and the e-Consent Procedure in the Landscape of Haematology.Clinics and practice · 2023Article
- The mediating effect of shared decision-making in enhancing patient satisfaction with participation in cancer clinical trials.Asia-Pacific journal of oncology nursing · 2023Article
- The role of immune checkpoint inhibitors in clinical practice: an analysis of the treatment patterns, survival and toxicity rates by sex.Journal of cancer research and clinical oncology · 2023Article
- Through the Lens of Patient Partners: Challenges in Accrual of Older Adults to NCI Clinical Trials.Journal of the National Cancer Institute. Monographs · 2022Article
- Exploring the Relationship between Medical Research Literacy and Respondents' Expressed Likelihood to Participate in a Clinical Trial.International journal of environmental research and public health · 2022Article
- Development of a Patient Decision Aid for the DAHANCA 35 Proton Radiotherapy Trial: An Iterative Development Process with User-Centered Design Elements.MDM policy & practiceArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few studies have explored the relationship between health literacy (HL) and trial participation. In this context, we aimed to study this relationship in French cancer patients. We used data from the French national VIe après le CANcer (VICAN) survey. Two questionnaire items focused on previous invitations to participate in clinical trials and subsequent enrollment. The Single Item Literacy Screener was used to measure functional HL. In total, 1954 cancer patients responded to both VICAN surveys (two and five years after diagnosis). Mean age was 54.1 ± 12.7 years at diagnosis, and 37.6% were classified as having limited HL. One in ten (10.3%) respondents reported having been previously invited to participate in a clinical trial. Of these, 75.5% had enrolled. Limited HL was associated with fewer trial invitations but not with enrollment once invited. Multivariate analysis confirmed the negative effect of limited HL on clinical trial invitation (adjOR = 0.55 (0.39 to 0.77), p < 0.001) after adjustment for multiple characteristics. Patients with limited HL received fewer invitations to participate in trials but were likely to enroll when asked. Addressing HL is necessary to create a more inclusive health system and to reduce inequalities not only in access to innovative cancer care, but to health inequalities in general.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.