Evidence map›Paper›PMID 35621636›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Cutaneous Involvement in Diseases with Plasma Cell Differentiation: Diagnostic Approach.

Magda Zanelli, Andrea Palicelli, Francesca Sanguedolce, Maurizio Zizzo, Alessandra Filosa, Linda Ricci, Camilla Cresta, Giovanni Martino, Alessandra Bisagni, Eleonora Zanetti and 7 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Magda ZanelliPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0002-8733-9933
Andrea PalicelliPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0003-2299-5160
Francesca SanguedolcePathology Unit, Policlinico Riuniti, University of Foggia, 71122 Foggia, Italy.
Maurizio ZizzoSurgical Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0001-9841-7856
Alessandra FilosaSection of Pathological Anatomy, United Hospitals Ancona, 60126 Ancona, Italy.
Linda RicciPathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
Camilla CrestaPathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.ORCID 0000-0002-9844-4763
Giovanni MartinoPathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
Alessandra BisagniPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Eleonora ZanettiPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0002-3483-130X
Francesco di DonatoDepartment of Biomedical and Neuromotor Sciences, School of Anatomic Pathology, Bellaria Hospital, University of Bologna, 40126 Bologna, Italy.
Beatrice MelliDepartment of Obstetrics and Gynaecology, Fertility Center, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0003-1366-2081
Alessandra SorianoGastroenterology Division, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Luca CiminoDepartment of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0001-7956-9950
Alberto CavazzaPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Lisa Francesca VivianPathology Unit, IRCCS Humanitas Research Hospital, 20089 Milan, Italy.
Stefano AscaniPathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
Azienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Perugia · ITUniversity of Modena and Reggio Emilia · ITIRCCS Humanitas Research Hospital · ITUniversity of Bologna · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoplasms with plasma cell differentiation may occasionally involve the skin. Cutaneous lesions may represent the first sign of an underlying systemic plasma cell malignancy, such as multiple myeloma, or the skin itself may be the primary site of occurrence of a hematological tumor with plasma cell differentiation. Starting from examples encountered in our daily practice, we discussed the diagnostic approach pathologists and clinicians should use when faced with cutaneous lesions with plasma cell differentiation. Cases of primary cutaneous marginal zone lymphoma, localized primary amyloidosis/amyloidoma, and cutaneous manifestations (secondary either to multiple myeloma or to plasmablastic lymphoma) are discussed, focusing on the importance of the adequate patient's work-up and precise clinicopathological correlation to get to the correct diagnosis and appropriate treatment. The pertinent literature has been reviewed, and the clinical presentation, pathological findings, main differential diagnoses, treatment, and outcome of neoplasms with plasma cell differentiation involving the skin are discussed.

Indexed as

Hematologic NeoplasmsMultiple MyelomaSkin NeoplasmsCell DifferentiationHumansamyloidomamultiple myelomaplasmablastic lymphomaplasma cell neoplasmsprimary cutaneous marginal zone lymphoma

Identifiers

PMID35621636
PMCPMC9139249
OpenAlexW4224318531

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.