ReviewCurrent oncology (Toronto, Ont.)2022
Intravascular Large B-Cell Lymphoma: A Review with a Focus on the Prognostic Value of Skin Involvement.
Review in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma.Internal medicine (Tokyo, Japan) · 2026Article
- An elusive diagnosis: Hemophagocytic variant of intravascular lymphoma masquerading as a drug eruption.Dermatology online journal · 2026Article
- Intravascular Lymphoma Associated with the Female Genital Tract-Diagnostic Considerations, Therapeutic Approaches, and Outcomes.Diseases (Basel, Switzerland) · 2026Review
- Clinical Warburg Effect in a primary cutaneous lymphoma.Clinical hematology international · 2026Article
- [Primary cutaneous B-cell lymphomas-an overview of established and novel aspects].Dermatologie (Heidelberg, Germany) · 2025Review
- Case Report: Neuropsychological Profile of a Patient With Intravascular Large B-Cell Lymphoma Following Infection and Vaccination.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Intravascular Large B-Cell Lymphoma Diagnosed After Recurrent Stroke: Case Report and Literature Review.Neurology international · 2025Article
- Primary pulmonary intravascular large B‑cell lymphoma: Indications from cytomorphology findings through CT‑guided puncture: A case report.Oncology letters · 2025Article
- Clinical manifestations and outcomes of patients with intravascular large B-cell lymphoma with neurological involvement: highlighting longitudinally extensive myelopathy as a distinct feature.BMJ neurology open · 2025Article
- Intravascular large B-cell lymphoma of the central nervous system with renal involvement: a case report and literature review.Frontiers in oncology · 2025Article
- Article
- Clinician's perspective on the diagnosis of primary cutaneous B-cell lymphoma.Dermatology reports · 2024Review
- A Case of Femoral Artery Aneurysm Caused by Methotrexate Associated Lymphoproliferative Disease.Cureus · 2024Article
- Cutaneous Intravascular Hematolymphoid Entities: A Review.Diagnostics (Basel, Switzerland) · 2024Review
- Intravascular large B-cell lymphoma as a covert trigger for hemophagocytic lymphohistiocytosis complicated with capillary leak syndrome: a case report and literature review.Frontiers in immunology · 2024Review
- Fever of unknown origin characterized by acute kidney injury and nephrotic syndrome diagnosed as intravascular large B-cell lymphoma of kidney: case report and literature review.International journal of clinical and experimental pathology · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravascular large B-cell lymphoma (IVLBCL) is an aggressive Non-Hodgkin lymphoma (NHL) characterised by the presence of neoplastic lymphoid cells within small- and medium-sized blood vessels. According to the clinical presentation, the current WHO classification distinguishes the 'classic' (formerly 'Western') from a hemophagocytic syndrome-associated (formerly 'Asian') variant. A third 'cutaneous' variant has been proposed, characterised by a good prognosis and unique clinical features. While laboratory findings can hint at diagnosis, symptoms are rather nonspecific, and deep skin biopsy supported by further measures such as bone marrow aspiration and positron emission tomography-computed tomography scanning is needed to make a definite diagnosis. Treatment is comprised of anthracycline-based chemotherapy supplemented with rituximab and central nervous system prophylaxis. While there are various prognostic models for NHL, only one is specific to IVLBCL, which does not sufficiently represent some patient groups, especially regarding the lack of differentiation within the patient collective with skin involvement. This underlines the necessity for the establishment of further prognostic models in particular for IVLBCL patients with cutaneous manifestations.
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