Evidence map›Paper›PMID 35621612›Full record

ArticleGels (Basel, Switzerland)2022

Preparation of Chitosan/Recombinant Human Collagen-Based Photo-Responsive Bioinks for 3D Bioprinting.

Yang Yang, Zixun Wang, Yuanyuan Xu, Jingjing Xia, Zhaoxian Xu, Shuai Zhu, Mingjie Jin

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Xeno-Free 3D Bioprinted Liver Model for Hepatotoxicity Assessment.International journal of molecular sciences · 2024
    Article
  8. Review
  9. Article
  10. Bioinks adapted forRSC advances · 2023
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yang YangDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, China.
Zixun WangSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.ORCID 0000-0002-7784-8718
Yuanyuan XuDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, China.
Jingjing XiaDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, China.
Zhaoxian XuSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Shuai ZhuSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Mingjie JinSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Nanjing University of Science and Technology · CNTsinghua University · CN

Funding

National High Technology Research and Development Program of China 2014AA022107
6 · The paper itself

Abstract

Collagen and chitosan are frequently used natural biomaterials in tissue engineering. However, most collagen is derived from animal tissue, with inconsistent quality and pathogen transmittance risks. In this context, we aimed to use a reliable Type-III recombinant human collagen (RHC) as an alternative biomaterial together with chitosan to develop novel photo-responsive bioinks for three-dimensional (3D) bioprinting. RHC was modified with methacrylic anhydride to obtain the RHC methacryloyl (RHCMA) and mixed with acidified chitosan (CS) to form composites CS-RHCMA. The characterizations demonstrated that the mechanical properties and the degradation of the bioinks were tunable by introducing the CS. The printabilities improved by adding CS to RHCMA, and various structures were constructed via extrusion-based 3D printing successfully. Moreover, in vitro tests confirmed that these CS-RHCMA bioinks were biocompatible as human umbilical vein endothelial cells (HUVECs) were sustained within the constructs post-printing. The results from the current study illustrated a well-established bioinks system with the potential to construct different tissues through 3D bioprinting.

Indexed as

3D printingbioinkschitosanrecombinant human collagentissue engineering

Identifiers

PMID35621612
PMCPMC9141723
OpenAlexW4280534100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.