Evidence map›Paper›PMID 35621594›Full record

ArticleGels (Basel, Switzerland)2022

Swelling and Mechanical Characterization of Polyelectrolyte Hydrogels as Potential Synthetic Cartilage Substitute Materials.

Johanna Romischke, Anton Scherkus, Michael Saemann, Simone Krueger, Rainer Bader, Udo Kragl, Johanna Meyer

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Johanna RomischkeIndustrial Chemistry, Institute of Chemistry, University of Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.ORCID 0000-0002-6715-5221
Anton ScherkusIndustrial Chemistry, Institute of Chemistry, University of Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.
Michael SaemannBiomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0003-1222-272X
Simone KruegerBiomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.
Rainer BaderBiomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.
Udo KraglIndustrial Chemistry, Institute of Chemistry, University of Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.ORCID 0000-0002-2507-7472
Johanna MeyerInstitute of Technical Chemistry, Leibniz University Hannover, Callinstraße 3-9, 30167 Hannover, Germany.ORCID 0000-0003-2557-4425
University of Rostock · DELeibniz University Hannover · DE

Funding

Deutsche Forschungsgemeinschaft SFB 1270/1 - 299150580Federal Ministry of Education and Research 03ZZ0933L
6 · The paper itself

Abstract

Hydrogels have become an increasingly interesting topic in numerous fields of application. In addition to their use as immobilization matrixes in (bio)catalysis, they are widely used in the medical sector, e.g., in drug delivery systems, contact lenses, biosensors, electrodes, and tissue engineering. Cartilage tissue engineering hydrogels from natural origins, such as collagen, hyaluronic acid, and gelatin, are widely known for their good biocompatibility. However, they often lack stability, reproducibility, and mechanical strength. Synthetic hydrogels, on the other hand, can have the advantage of tunable swelling and mechanical properties, as well as good reproducibility and lower costs. In this study, we investigated the swelling and mechanical properties of synthetic polyelectrolyte hydrogels. The resulting characteristics such as swelling degree, stiffness, stress, as well as stress-relaxation and cyclic loading behavior, were compared to a commercially available biomaterial, the ChondroFiller

Indexed as

cartilage lesioncompressioncyclic loadinghydrogelmechanical characterizationpolyelectrolytestress-relaxationsubstitute materialswellingsynthetic polymer

Identifiers

PMID35621594
PMCPMC9141488
OpenAlexW4280517349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.