ArticleGels (Basel, Switzerland)2022
Pilot Study of Polymerization Dynamics in nMAG Dose Gel.
Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Ultra-High Dose Rate Electron Beam Dosimetry Using Ag Nanoparticle-Enhanced nPAG and NIBMAGAT Gels.Gels (Basel, Switzerland) · 2025Article
- Gel Dosimetry.Gels (Basel, Switzerland) · 2023Article
- Investigation of Colored Film Indicators for the Assessment of the Occasional Radiation Exposure.Gels (Basel, Switzerland) · 2023Article
- Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review.Gels (Basel, Switzerland) · 2022Review
- The Impact of Temporal Changes in Irradiated nMAG Polymer Gels on Their Applicability in Small Field Dosimetry in Radiotherapy.Gels (Basel, Switzerland) · 2022Article
- Radiation Dosimetry by Use of Radiosensitive Hydrogels and Polymers: Mechanisms, State-of-the-Art and Perspective from 3D to 4D.Gels (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The essential component of modern radiation therapy is the application of steep dose gradients during patient treatment in order to maximize the radiation dose to the target volume and protect neighboring heathy tissues. However, volumetric dose distribution in an irradiated target is still a bottleneck of dose verification in modern radiotherapy. Dose gels are almost the only known dosimetry tool which allows for the evaluation of dose distribution in the irradiated volume due to gel's polymerization upon irradiation. The accuracy of dose gel dosimetry has its own obstacle, which is related to the continuation of the gel's polymerization after the radiation treatment procedure is finished. In this article, a method to monitor the polymerization dynamics of dose gels in real-time is proposed using a modified optical spectrometry system. Using the proposed method, the changes of the optical characteristics of irradiated nMAG dose gels in situ were assessed. The investigation revealed that the detectable polymerization in dose gel proceeds up to 6 h after irradiation. This time is significantly shorter compared with a commonly recommended 24 h waiting time allocated for polymer gel to settle. It was also found that dose rate significantly influences the temporal response of the nMAG dosimeter. By increasing the irradiation dose rate by a factor of 2, the time needed for the polymerization process to settle was increased by 22%. Identification of the gel's post-irradiation polymerization time interval and its dependence on irradiation parameters will contribute to more accurate dose verification using dose gel dosimetry.
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Registered trials
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