Evidence map›Paper›PMID 35621504›Full record

ReviewBioengineering (Basel, Switzerland)2022

Applications of Photodynamic Therapy in Endometrial Diseases.

Gabriela Correia-Barros, Beatriz Serambeque, Maria João Carvalho, Carlos Miguel Marto, Marta Pineiro, Teresa M V D Pinho E Melo, Maria Filomena Botelho, Mafalda Laranjo

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Targeted photodynamic neutralization of SARS-CoV-2 mediated by singlet oxygen.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gabriela Correia-BarrosInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
Beatriz SerambequeInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-3634-859X
Maria João CarvalhoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9409-5466
Carlos Miguel MartoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9269-5417
Marta PineiroCoimbra Chemistry Centre (CQC)-Institute of Molecular Sciences (IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-7460-3758
Teresa M V D Pinho E MeloCoimbra Chemistry Centre (CQC)-Institute of Molecular Sciences (IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-3256-4954
Maria Filomena BotelhoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-7202-1650
Mafalda LaranjoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0689-6007
University of Coimbra · PT

Funding

Fundação para a Ciência e Tecnologia COMPETE-FEDER (POCI-01-0145-FEDER-007440)Fundação para a Ciência e Tecnologia PhD fellowship awarded to Beatriz Serambeque (2020.07672.BD)Fundação para a Ciência e Tecnologia PTDC/QUI-QOR/0103/2021Fundação para a Ciência e Tecnologia Strategic Projects UID/NEU/04539/2019, UIDB/04539/2020, UIDP/04539/2020Fundação para a Ciência e Tecnologia UIDB/00313/2020 and UIDP/00313/2020
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a medical procedure useful for several benign conditions (such as wound healing and infections) and cancer. PDT is minimally invasive, presents few side effects, good scaring, and is able to minimal tissue destruction maintaining organ anatomy and function. Endoscopic access to the uterus puts PDT in the spotlight for endometrial disease treatment. This work systematically reviews the current evidence of PDT's potential and usefulness in endometrial diseases. Thus, this narrative review focused on PDT applications for endometrial disease, including reports regarding in vitro, ex vivo, animal, and clinical studies. Cell lines and primary samples were used as in vitro models of cancer, adenomyosis and endometrioses, while most animal studies focused the PDT outcomes on endometrial ablation. A few clinical attempts are known using PDT for endometrial ablation and cancer lesions. This review emphasises PDT as a promising field of research. This therapeutic approach has the potential to become an effective conservative treatment method for endometrial benign and malignant lesions. Further investigations with improved photosensitisers are highly expected.

Indexed as

animalendometrial neoplasmsendometriummodelsphotochemotherapyphotodynamic therapytherapeutics

Identifiers

PMID35621504
PMCPMC9138084
OpenAlexW4281397802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.