Evidence map›Paper›PMID 35621461›Full record

ArticleBioengineering (Basel, Switzerland)2022

Prediction of Glucose Concentration in Children with Type 1 Diabetes Using Neural Networks: An Edge Computing Application.

Federico D'Antoni, Lorenzo Petrosino, Fabiola Sgarro, Antonio Pagano, Luca Vollero, Vincenzo Piemonte, Mario Merone

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Pediatrics 4.0: the Transformative Impacts of the Latest Industrial Revolution on Pediatrics.Health care analysis : HCA : journal of health philosophy and policy · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Federico D'AntoniUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0001-7377-5462
Lorenzo PetrosinoUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Fabiola SgarroUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Antonio PaganoUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Luca VolleroUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-6928-0157
Vincenzo PiemonteUnit of Chemical Engineering, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-2421-3938
Mario MeroneUnit of Computer Systems and Bioinformatics, Department of Engineering, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-9406-2397
Università Campus Bio-Medico · IT

Funding

Progetti di Gruppi di Ricerca 2020 grant number: A0375E0196
6 · The paper itself

Abstract

backgroundType 1 Diabetes Mellitus (T1D) is an autoimmune disease that can cause serious complications that can be avoided by preventing the glycemic levels from exceeding the physiological range. Straightforwardly, many data-driven models were developed to forecast future glycemic levels and to allow patients to avoid adverse events. Most models are tuned on data of adult patients, whereas the prediction of glycemic levels of pediatric patients has been rarely investigated, as they represent the most challenging T1D population.

methodsA Convolutional Neural Network (CNN) and a Long Short-Term Memory (LSTM) Recurrent Neural Network were optimized on glucose, insulin, and meal data of 10 virtual pediatric patients. The trained models were then implemented on two edge-computing boards to evaluate the feasibility of an edge system for glucose forecasting in terms of prediction accuracy and inference time.

resultsThe LSTM model achieved the best numeric and clinical accuracy when tested in the

conclusionBoth models effectively predict glucose in pediatric patients in terms of numerical and clinical accuracy. The edge implementation did not show a significant performance decrease, and the inference time was largely adequate for a real-time application.

Indexed as

artificial intelligencedecision support systemdiabetesedge computingglucose predictionneural networkpediatricsprecision medicinetime-series forecasting

Identifiers

PMID35621461
PMCPMC9137786
OpenAlexW4224302537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.