Evidence map›Paper›PMID 35621361›Full record

ArticleAnalytical chemistry2022

Investigating the Lipid Selectivity of Membrane Proteins in Heterogeneous Nanodiscs.

James E Keener, Hiruni S Jayasekera, Michael T Marty

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James E KeenerDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Hiruni S JayasekeraDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Michael T MartyDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-8115-1772
University of Arizona · US

Funding

Unravelling Membrane Protein-Lipid Interactions using Nanodiscs and Mass SpectrometryR35GM128624 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Michael T Marty · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM128624
6 · The paper itself

Abstract

The structure and function of membrane proteins can be significantly impacted by the surrounding lipid environment, but membrane protein-lipid interactions in lipid bilayers are often difficult to study due to their transient and polydisperse nature. Here, we used two native mass spectrometry (MS) approaches to investigate how the

Indexed as

AquaporinsCation Transport ProteinsEscherichia coli ProteinsNanostructuresEscherichia coliLipid BilayersMembrane LipidsMembrane ProteinsPhosphatidylcholinesPhosphatidylethanolaminesPhosphatidylglycerolsAmtB protein, E coliaqpZ protein, E coliAquaporinsCation Transport ProteinsEscherichia coli ProteinsLipid BilayersMembrane LipidsMembrane ProteinsPhosphatidylcholinesPhosphatidylethanolaminesPhosphatidylglycerols

Identifiers

PMID35621361
PMCPMC9197995
OpenAlexW4281622997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.