Evidence map›Paper›PMID 35621286›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2022

A survey of physician perception and practices regarding pharmacological thromboprophylaxis during chemotherapy for bladder cancer.

Andrew Amenyogbe, Francis Lemire, David Yachnin, Marc Carrier, Kristen McAlpine, Rodney H Breau, Dominick Bossé, Tzu-Fei Wang, Christopher Morash, Ilias Cagiannos and 1 more

Abstract read
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Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrew AmenyogbeDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.
Francis LemireDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.
David YachninThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Marc CarrierThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Kristen McAlpineDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Rodney H BreauDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.
Dominick BosséThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Tzu-Fei WangThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Christopher MorashDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.
Ilias CagiannosDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.
Luke T LavalléeDivision of Urology, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with advanced bladder cancer receiving chemotherapy have a high risk of venous thromboembolism (VTE); however, we hypothesized these patients were not routinely offered thromboprophylaxis. The objective of this study was to characterize practice patterns and perceptions of Canadian urologic and medical oncologists, and to identify research needs regarding thromboprophylaxis for patients with bladder cancer.

methodsAn online survey was distributed to Canadian urologic and medical oncologists who manage advanced bladder cancer. The survey explored physician opinions regarding VTE rates, risk stratification scores, thromboprophylaxis use in different treatment settings, and interest in clinical trials.

resultsSeventy physicians were invited and 36 (51%) completed the survey, including 20 (56%) urologic oncologists and 16 (44%) medical oncologists. Most respondents (35; 97%) believed that exposure to platinum chemotherapy increases VTE risk. For patients receiving neoadjuvant chemotherapy, 34 (94%) respondents estimated the risk of VTE to be 10% or higher, yet 25 (69%) indicated they do not routinely recommend thromboprophylaxis. Physicians frequently (10; 40%) defer the decision to another physician, while eight (32%) believe there is not enough evidence to guide best management. Similar responses were obtained for metastatic patients. Almost all (94%) respondents were interested in participating in a thromboprophylaxis trial for patients with bladder cancer.

conclusionsPatients with bladder cancer receiving chemotherapy in Canada are not routinely offered thromboprophylaxis. We found strong interest among Canadian oncologists to participate in clinical trials examining this topic.

Identifiers

PMID35621286
PMCPMC9565069

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.