Evidence map›Paper›PMID 35621237›Full record

ArticleChemical communications (Cambridge, England)2022

Encoding latent SuFEx reactive meta-fluorosulfate tyrosine to expand covalent bonding of proteins.

Paul C Klauser, Viktoriya Y Berdan, Li Cao, Lei Wang

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Diversity Oriented Clicking for Modular Synthesis.Nature reviews. Methods primers · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul C KlauserDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, California 94158, USA. Lei.Wang2@ucsf.edu.ORCID http://orcid.org/0000-0001-7900-7659
Viktoriya Y BerdanDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, California 94158, USA. Lei.Wang2@ucsf.edu.
Li CaoDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, California 94158, USA. Lei.Wang2@ucsf.edu.
Lei WangDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, California 94158, USA. Lei.Wang2@ucsf.edu.ORCID http://orcid.org/0000-0002-5859-2526

Funding

Covalent Protein Binders for Cancer Research and TherapyR01CA258300 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, LEI · 2021 to 2025
$2.0M
NCI NIH HHS R01 CA258300
6 · The paper itself

Abstract

The introduction of new covalent bonds into proteins is affording novel avenues for protein research and applications, yet it remains difficult to generate covalent linkages at all possible sites and across diverse protein classes. Herein, we genetically encoded

Indexed as

ProteinsTyrosineAmino AcidsHistidineLysineAmino AcidsHistidineLysineProteinsTyrosine

Identifiers

PMID35621237
PMCPMC9816398

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.