Evidence map›Paper›PMID 35621200›Full record

ArticleJournal of the American Heart Association2022

Clinical Impact of Heart Team Decisions for Patients With Complex Valvular Heart Disease: A Large, Single-Center Experience.

Francesco Burzotta, Francesca Graziani, Carlo Trani, Cristina Aurigemma, Piergiorgio Bruno, Antonella Lombardo, Giovanna Liuzzo, Marialisa Nesta, Gaetano Antonio Lanza, Enrico Romagnoli and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The multidisciplinary heart team: gatekeeper or last resort?Proceedings (Baylor University. Medical Center)
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Francesco BurzottaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0002-6569-9401
Francesca GrazianiFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0002-4520-5689
Carlo TraniFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Cristina AurigemmaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Piergiorgio BrunoFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Antonella LombardoFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0003-3162-1830
Giovanna LiuzzoFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Marialisa NestaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Gaetano Antonio LanzaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0003-2187-6653
Enrico RomagnoliFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0003-1611-7708
Gabriella LocorotondoFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0001-8589-7328
Antonio Maria LeoneFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Natalia PavoneFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Claudio SpallettaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Gemma PelargonioFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Tommaso SannaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0002-5760-6885
Nadia AspromonteFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.ORCID 0000-0002-0369-2052
Franco CavaliereFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Filippo CreaFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Massimo MassettiFondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background A multidisciplinary approach might be pivotal for the management of patients with valvular heart disease (VHD), but clinical outcome data are lacking. Methods and Results At our institution, since 2014, internal guidelines recommended heart team consultations for patients with VHD. The clinical/echocardiographic characteristics, treatment recommendations, performed treatment, and early clinical outcomes of consecutive, hospitalized patients with VHD undergoing heart team evaluation were collected. Surgical risk was prospectively assessed by the EuroSCORE II and STS-PROM. The primary end point of the study was early mortality. A total of 1004 patients with VHD with high clinical complexity (mean age, 75 years; mean EuroSCORE II, 9.4%; mean STS-PROM, 5.6%; 48% ischemic heart disease; 29% chronic kidney disease, 9% oncologic/hematologic diseases) were enrolled. The heart team recommended an interventional treatment for 807 (80%) patients and conservative management for 197 (20%) patients. Management crossovers occurred in only 5% of patients. The recommended intervention was cardiac surgery for 230 (23%) patients, percutaneous treatment in 516 (51%) patients, and hybrid treatment in 61 (6%) patients. Early mortality occurred in 24 patients (2.4%) and was independently predicted by aortic stenosis, left ventricular ejection fraction, pulmonary artery systolic pressure, and conservative management recommendation. In patients referred to treatment, observed early mortality (1.7%) was significantly lower (

Indexed as

Aortic Valve StenosisHeart Valve DiseasesAgedEchocardiographyHumansRisk FactorsStroke VolumeVentricular Function, Leftcardiac surgeryheart teamhybrid interventionsmortalityprecision medicineTAVIvalvular heart disease

Identifiers

PMID35621200
PMCPMC9238748
OpenAlexW4282045174

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.