Evidence map›Paper›PMID 35621198›Full record

ArticleJournal of the American Heart Association2022

Patient- and Process-Related Contributors to the Underuse of Aortic Valve Replacement and Subsequent Mortality in Ambulatory Patients With Severe Aortic Stenosis.

Laura Flannery, Muhammad Etiwy, Alexander Camacho, Ran Liu, Nilay Patel, Arpi Tavil-Shatelyan, Varsha K Tanguturi, Jacob P Dal-Bianco, Evin Yucel, Rahul Sakhuja and 6 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Beyond Referral: Symptoms Still Matter in Severe Aortic Stenosis.Structural heart : the journal of the Heart Team · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Laura FlanneryCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Muhammad EtiwyCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Alexander CamachoCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.ORCID 0000-0002-8832-5744
Ran LiuCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Nilay PatelCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Arpi Tavil-ShatelyanCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Varsha K TanguturiCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Jacob P Dal-BiancoCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Evin YucelCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.ORCID 0000-0002-7074-6380
Rahul SakhujaCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Arminder S JassarDivision of Cardiac Surgery Department of Surgery Massachusetts General HospitalHarvard Medical School Boston MA.
Nathaniel B LangerDivision of Cardiac Surgery Department of Surgery Massachusetts General HospitalHarvard Medical School Boston MA.ORCID 0000-0002-3451-8735
Ignacio InglessisCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Jonathan J PasseriCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Judy HungCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.ORCID 0000-0003-3737-7584
Sammy ElmariahCardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.ORCID 0000-0002-8013-8733

Funding

Improving Mitral Compensation In Ischemic RegurgitationR01HL141917 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI AIKAWA, ELENA, BISCHOFF, JOYCE E. · 2018 to 2021
$5.6M
Multi-Omic Markers of Cardiac Function and Structure within the Pressure Overloaded HeartR01HL151838 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ELMARIAH, SAMMY · 2020 to 2024
$3.6M
NHLBI NIH HHS R01 HL141917NHLBI NIH HHS R01 HL151838
6 · The paper itself

Abstract

Background Many patients with severe aortic stenosis (AS) and an indication for aortic valve replacement (AVR) do not undergo treatment. The reasons for this have not been well studied in the transcatheter AVR era. We sought to determine how patient- and process-specific factors affected AVR use in patients with severe AS. Methods and Results We identified ambulatory patients from 2016 to 2018 demonstrating severe AS, defined by aortic valve area [Formula: see text]1.0 cm

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationAortic ValveFemaleHumansMalePropensity ScoreSeverity of Illness IndexStroke VolumeTreatment OutcomeVentricular Function, Leftaortic stenosisaortic valve replacementsurvivaltreatment predictors

Identifiers

PMID35621198
PMCPMC9238693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.