Evidence map›Paper›PMID 35620851›Full record

ArticleChronic respiratory disease

Prevalence of chronic cough and patient characteristics in adults in Spain: A population-based cross-sectional survey.

Javier Domínguez-Ortega, Vicente Plaza, Vicky W Li, Eileen Fonseca, Luis Cea-Calvo, Ashley Martin, Marta Sánchez-Jareño, Joanne E Brady, Jonathan Schelfhout

Open access · goldAbstract read
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Efficacy and safety of gefapixant for chronic cough: a meta-analysis of randomised controlled trials.European respiratory review : an official journal of the European Respiratory Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Javier Domínguez-OrtegaAllergy Department, La Paz University Hospital, IdiPAZ, Madrid, Spain.
Vicente PlazaCIBER of Respiratory Diseases, CIBERES, Madrid, Spain.
Vicky W LiCerner Enviza, New York, NY, USA.
Eileen FonsecaMerck & Co., Inc. Rahway, NJ, USA.
Luis Cea-CalvoMedical Affairs, MSD, Madrid, Spain.
Ashley MartinCerner Enviza, New York, NY, USA.
Marta Sánchez-JareñoMedical Affairs, MSD, Madrid, Spain.
Joanne E BradyMerck & Co., Inc. Rahway, NJ, USA.
Jonathan SchelfhoutMerck & Co., Inc. Rahway, NJ, USA.
Merck & Co., Inc., Rahway, NJ, USA (United States) · USCerner (United States) · USMSD (Spain) · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic cough (CC) represents a significant health burden. This study assessed the prevalence of CC (defined as per international guidelines as cough duration >8 weeks) in Spanish adults and compared characteristics between CC and non-CC cohorts.

methodsCC cohorts were compiled using data from adult respondents to the 2020 Spanish cross-sectional online National Health and Wellness Survey (NHWS). Using propensity scores, respondents experiencing CC during their lifetime and the previous 12 months were matched 3:1 to respondents without CC and their health characteristics were compared. The number of Spanish adults affected with CC was estimated using weighted CC prevalence.

resultsCC during their lifetime or the previous 12 months was experienced by 579 (8.2%) and 389 (5.5%) of 7074 NHWS respondents, of whom 233 (38.5%) and 171 (44.0%), respectively, had physician-diagnosed CC. Based on weighted prevalence rates, lifetime and 12-month CC were estimated to affect ≈3.3 million and ≈2.2 million Spanish adults, respectively. Relative to the non-CC cohort, the 12-month CC cohort consistently demonstrated poorer health status, poorer mental health, greater healthcare utilization, and lower productivity at work and home.

conclusionThis study contributes novel data regarding the prevalence of CC in Spain, suggests that CC is underdiagnosed, and reflects that CC and related comorbidities inflict a significant health burden in the affected population.

Indexed as

CoughQuality of LifeAdultChronic DiseaseCross-Sectional StudiesHumansPrevalenceSpainChronic coughepidemiologyprevalencesurvey

Identifiers

PMID35620851
PMCPMC9150240
OpenAlexW4282942581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.