Evidence map›Paper›PMID 35620656›Full record

ReviewJournal of tissue engineering

Decellularization for the retention of tissue niches.

Deana Moffat, Kaiming Ye, Sha Jin

Abstract readReview
In one paragraph

Review in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Supercritical COMaterials today. Bio · 2026
    Article
  5. Article
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  7. Article
  8. Extracellular stiffness regulates cell fate determination and drives the emergence of evolutionary novelty in the teleost heart.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
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  17. Article
  18. Decellularized testicular bio-scaffolds driveFrontiers in bioengineering and biotechnology · 2026
    Article
  19. Review
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deana MoffatDepartment of Biomedical Engineering, Binghamton University, State University of New York (SUNY), Binghamton, NY, USA.
Kaiming YeDepartment of Biomedical Engineering, Binghamton University, State University of New York (SUNY), Binghamton, NY, USA.
Sha JinDepartment of Biomedical Engineering, Binghamton University, State University of New York (SUNY), Binghamton, NY, USA.ORCID https://orcid.org/0000-0002-8033-8110

Funding

Generation of islet organoids in oxygenated scaffoldsR15EB027391 · NIBIB · STATE UNIVERSITY OF NY,BINGHAMTON · PI JIN, SHA · 2019 to 2019
$450k
NIBIB NIH HHS R15 EB027391
6 · The paper itself

Abstract

Decellularization of natural tissues to produce extracellular matrix is a promising method for three-dimensional scaffolding and for understanding microenvironment of the tissue of interest. Due to the lack of a universal standard protocol for tissue decellularization, recent investigations seek to develop novel methods for whole or partial organ decellularization capable of supporting cell differentiation and implantation towards appropriate tissue regeneration. This review provides a comprehensive and updated perspective on the most recent advances in decellularization strategies for a variety of organs and tissues, highlighting techniques of chemical, physical, biological, enzymatic, or combinative-based methods to remove cellular contents from tissues. In addition, the review presents modernized approaches for improving standard decellularization protocols for numerous organ types.

Indexed as

biological methodchemical methodDecellularizationenzymesextracellular matrixphysical methodtissue and organ

Identifiers

PMID35620656
PMCPMC9128068

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.