Evidence map›Paper›PMID 35620638›Full record

ArticleRegenerative therapy2022

Gli

Long Shi, Xiang Gao, Yue Bi, Meng Li, Huanhuan Sun, Xiaochao Tian, Wei Bi

Open access · goldAbstract read
In one paragraph

Article in Regenerative therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Long ShiDepartment of Vascular Surgery, The Second Hospital of Hebei Medical University, China.
Xiang GaoDepartment of Vascular Surgery, The Second Hospital of Hebei Medical University, China.
Yue BiDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, China.
Meng LiDepartment of Vascular Surgery, The Second Hospital of Hebei Medical University, China.
Huanhuan SunDepartment of Vascular Surgery, The Second Hospital of Hebei Medical University, China.
Xiaochao TianDepartment of Cardiology, The Second Hospital of Hebei Medical University, China.
Wei BiDepartment of Vascular Surgery, The Second Hospital of Hebei Medical University, China.
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: There are many researches on using bone marrow mesenchymal stem cells (BMSCs) in the treatment of acute kidney injury (AKI), which has certain effects, but the mechanism of action is still unclear. Previous researches show that glioma-associated oncogene homolog 1 (Gli 1) can promote the proliferation and migration of cells, which can also promote renal fibrosis. Therefore, we investigate the influence of Gli-regulated BMSCs on repairing AKI and renal fibrosis induced by limb Ischemia-Reperfusion (I/R). Methods: The Crispr-Cas9 technique was adopted to knock out the Gli1 gene from the mouse BMSCs according to green fluorescent tracing, and the BMSCs (BMSCs-Gli Results: The BMSCs-Gli

Indexed as

Acute kidney injuryBMSCsI/R injuryRenal fibrosis

Identifiers

PMID35620638
PMCPMC9111922
OpenAlexW4280575907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.