ArticleFrontiers in pain research (Lausanne, Switzerland)2022
Understanding Pain and Trauma Symptoms in Veterans From Resting-State Connectivity: Unsupervised Modeling.
Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- PTSD subtypes and their underlying neural biomarkers: a systematic review.Psychological medicine · 2025Pooled it
- Amygdala and nucleus accumbens activation are associated with treatment choice in knee osteoarthritis: an fMRI study.Arthroplasty (London, England) · 2026Article
- Brain mechanisms of pain anticipation in chronic low back pain: Insights into phenotypical responses to mind-body therapy.The journal of pain · 2026Article
- Expectation of pain and relief: A dynamical model of the neural basis for pain-trauma co-morbidity.Neuroscience and biobehavioral reviews · 2024Review
- The Role of the Insula in Chronic Pain and Associated Structural Changes: An Integrative Review.Cureus · 2024Review
- Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Unsupervised learning for prognostic validity in patients with chronic pain in transdisciplinary pain care.Scientific reports · 2023Article
- Distal neuropathic pain in HIV is associated with functional connectivity patterns in default mode and salience networks.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Trauma and posttraumatic stress are highly comorbid with chronic pain and are often antecedents to developing chronic pain conditions. Pain and trauma are associated with greater utilization of medical services, greater use of psychiatric medication, and increased total cost of treatment. Despite the high overlap in the clinic, the neural mechanisms of pain and trauma are often studied separately. In this study, resting-state functional magnetic resonance imaging (rs-fMRI) scans were completed among a diagnostically heterogeneous sample of veterans with a range of back pain and trauma symptoms. Using Group Iterative Multiple Model Estimation (GIMME), an effective functional connectivity analysis, we explored an unsupervised model deriving subgroups based on path similarity in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.