Evidence map›Paper›PMID 35620595›Full record

ArticleFrontiers in physiology2022

CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons.

Tayla A Rees, Andrew F Russo, Simon J O'Carroll, Debbie L Hay, Christopher S Walker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. PACAP versus CGRP in migraine: From mouse models to clinical translation.Cephalalgia : an international journal of headache · 2025
    Review
  4. Review
  5. Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Calcitonin/PACTrends in pharmacological sciences · 2023
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tayla A ReesSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Andrew F RussoDepartment of Molecular Physiology and Biophysics, Center for the Prevention and Treatment of Visual Loss, Veterans Administration Health Center, Department of Neurology, University of Iowa, Iowa City, IA, United States.
Simon J O'CarrollDepartment of Anatomy and Medical Imaging and Centre for Brain Research, Faculty of Medical and Health Science, University of Auckland, Auckland, New Zealand.
Debbie L HayMaurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Christopher S WalkerSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Maurice Wilkins Centre · NZUniversity of Auckland · NZUniversity of Iowa · US

Funding

Perivascular mechanisms of CGRP-induced migraine symptomsR01NS075599 · NINDS · UNIVERSITY OF IOWA · PI RUSSO, ANDREW F · 2011 to 2023
$5.0M
Target validation of a novel CGRP receptor in migraineRF1NS113839 · NINDS · UNIVERSITY OF IOWA · PI HAY, DEBBIE L, RUSSO, ANDREW F · 2019 to 2019
$3.1M
NINDS NIH HHS R01 NS075599NINDS NIH HHS RF1 NS113839
6 · The paper itself

Abstract

The neuropeptide calcitonin gene-related peptide (CGRP) is expressed in the trigeminal ganglia, a key site in craniofacial pain and migraine. CGRP potently activates two receptors: the CGRP receptor and the AMY

Indexed as

amylinamylin 1 (AMY1)CGRP—calcitonin gene-related peptideG protein-coupled receptorheadachemigrainetrigeminal ganglia

Identifiers

PMID35620595
PMCPMC9128745
OpenAlexW4280560611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.