ArticleArthroplasty today2022
Osseointegration Following Transfemoral Amputation After Infected Total Knee Replacement: A Case Series of 10 Patients With a Mean Follow-up of 5 Years.
Article in Arthroplasty today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Meta-analytic evaluation of complications and longevity of bone-anchored prostheses in lower extremity amputees: does design matter?Musculoskeletal surgery · 2026Pooled it
- Wearing Time, Quality of Life, and Complications of Lower Limb Bone-anchored Prostheses: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Sequential Transcutaneous Mechanical Femoral Lengthening of a Profoundly Short Skeletal Residuum and Subsequent Successful Transfemoral Osseointegration: A Case Report Describing a Novel Endo-Exo Intramedullary Stump Lengthening Device.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Breaking Barriers-The Promise and Challenges of Limb Osseointegration Surgery.Medicina (Kaunas, Lithuania) · 2025Article
- Lower Extremity Osseointegration Postoperative Rehabilitation Protocols: A Scoping Review.Physical therapy · 2025Article
- Transfemoral Osseointegration in Association With Total Hip Replacement: Observational Cohort Study of Patients With Follow-Up Exceeding 2 Years.Arthroplasty today · 2024Article
- Complications Following Osseointegrated Transfemoral and Transtibial Implants: A Systematic Review.Cureus · 2024Review
- Bone-anchored prostheses for lower limb amputation in a French cohort with 1-15 years of follow-up: implant survival rates, mechanical complications, and reported outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Bone density changes after five or more years of unilateral lower extremity osseointegration: Observational cohort study.Bone reports · 2023Article
- Techniques to Remove Press-Fit Osseointegration Implants.JBJS essential surgical techniquesArticle
- Transcutaneous Osseointegration for Amputees as a Result of Sepsis Management: A Case Series of Nine Patients with a Mean Follow-up of 4 Years.Strategies in trauma and limb reconstructionReview
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Management of total knee replacement (TKR) infection may sometimes prompt knee fusion (KF) or transfemoral amputation (TFA), both associated with low mobility and quality of life (QOL). Transcutaneous osseointegration for amputees provides superior mobility and QOL vs traditional socket prostheses but has not been studied for patients with a history of infected TKR. This study investigates the following hypothesis: Patients who have had TFA or KF following infected TKR achieve better mobility and QOL following transfemoral osseointegration. Material and methods: A retrospective evaluation of the prospectively maintained registry identified 10 patients who had prior infected TKR. The mobility assessments (patient daily prosthesis wear time, K-level, Timed Up and Go, 6-Minute Walk Test) and QOL surveys (Questionnaire for Persons with a Transfemoral Amputation Global, Mobility, and Problem scores) were compared preoperatively and after at least 2 years. Complications requiring an additional surgery were also evaluated. Results: Daily wear hours, K-level, and 6-Minute Walk Test and Questionnaire for Persons with a Transfemoral Amputation Global and Problem scores significantly improved ( Conclusion: Transfemoral osseointegration confers significantly better mobility and QOL vs KF or a TFA with traditional socket prostheses following infected TKR. Technique improvements to prevent subsequent surgeries may provide an increasingly streamlined experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.