Evidence map›Paper›PMID 35620573›Full record

ArticleOxidative medicine and cellular longevity2022

In Vitro Evaluation of Antibacterial, Antioxidant, and Antidiabetic Activities and Glucose Uptake through 2-NBDG by Hep-2 Liver Cancer Cells Treated with Green Synthesized Silver Nanoparticles.

Shahnaz Majeed, Mohammed Danish, Norul Aini Zakariya, Rokiah Hashim, Mohammed Tahir Ansari, Saad Alkahtani, Md Saquib Hasnain

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shahnaz MajeedFaculty of Pharmacy and Health, Universiti Kuala Lumpur, Royal College of Medicine, Ipoh Perak, Malaysia 30450.ORCID https://orcid.org/0000-0002-0247-7553
Mohammed DanishBioresource Technology Section, School of Industrial Technology, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Norul Aini ZakariyaFaculty of Pharmacy and Health, Universiti Kuala Lumpur, Royal College of Medicine, Ipoh Perak, Malaysia 30450.
Rokiah HashimBioresource Technology Section, School of Industrial Technology, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Mohammed Tahir AnsariSchool of Pharmacy, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih, 43500 Selangor, Malaysia.
Saad AlkahtaniDepartment of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0001-7381-5110
Md Saquib HasnainDepartment of Pharmacy, Palamau Institute of Pharmacy, Chianki, Daltonganj, 822102 Jharkhand, India.ORCID https://orcid.org/0000-0002-1902-8500
Universiti Sains Malaysia · MYUniversity of Kuala Lumpur · MYKing Saud University · SAUniversity of Nottingham Malaysia Campus · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alarming rise in diabetes owing to drug resistance necessitates the implementation of prompt countermeasures in the treatment module of diabetes. Due to their unique physicochemical features, silver nanoparticles may have potential applications in the medical and pharmaceutical industries. Silver nanoparticles (AgNPs) were synthesized from the culture filtrate of Salmonella enterica (ATCC-14028). UV-Vis spectrophotometry, FTIR, SEM, and energy dispersive X-rays were used in the characterization of the nanoparticles. Transmission electron microscopy (TEM) revealed that AgNPs are spherical and highly scattered and vary in size from 7.18 nm to 13.24 nm. AgNP stability and protein loss were confirmed by thermogravimetric analysis (TGA) at different temperatures. The AgNPs had excellent antibacterial activity and a strong synergistic effect against methicillin-resistant bacteria Staphylococcus aureus (MRSA) ATCC-4330 and Streptococcus epidermis (MRSE) ATCC-51625. The DPPH experiment revealed that the AgNPs had high antioxidant activity. The antidiabetic assay revealed that these AgNPs had an IC50 for alpha-amylase of 428.60

Indexed as

Liver NeoplasmsMetal Nanoparticles4-Chloro-7-nitrobenzofurazanAnti-Bacterial AgentsAntioxidantsDeoxyglucoseGlucoseHumansHypoglycemic AgentsPlant ExtractsSilver2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose4-Chloro-7-nitrobenzofurazanAnti-Bacterial AgentsAntioxidantsDeoxyglucoseGlucoseHypoglycemic AgentsPlant ExtractsSilver

Identifiers

PMID35620573
PMCPMC9129982
OpenAlexW4280501695

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.