Evidence map›Paper›PMID 35620441›Full record

ArticleiScience2022

The E3 ubiquitin ligase RNF216/TRIAD3 is a key coordinator of the hypothalamic-pituitary-gonadal axis.

Arlene J George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C Hoffiz, Christopher B Ware, Ning Fang, Anne Z Murphy, Erik Hrabovszky, Desiree Wanders and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Arlene J GeorgeNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Bin DongDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Hannah LailDepartment of Nutrition, Georgia State University, 140 Decatur St SE, Atlanta, GA 30303, USA.
Morgan GomezNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Yarely C HoffizNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Christopher B WareNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Ning FangDepartment of Chemistry, Georgia State University, 50 Decatur St SE., Atlanta, GA 30302, United States.
Anne Z MurphyNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Erik HrabovszkyLaboratory of Reproductive Neurobiology, Institute of Experimental Medicine, Budapest, Hungary.
Desiree WandersDepartment of Nutrition, Georgia State University, 140 Decatur St SE, Atlanta, GA 30303, USA.
Angela M MabbNeuroscience Institute, Georgia State University, 100 Piedmont Avenue, Atlanta, GA 30303, USA.
Georgia State University · USHUN-REN Institute of Experimental Medicine · HUUniversity of Arkansas at Fayetteville · US

Funding

Impact of advanced age on opiate analgesiaR01DA041529 · NIDA · GEORGIA STATE UNIVERSITY · PI MURPHY, ANNE Z · 2017 to 2021
$1.8M
Probing Cellular Membrane Processes by Single Particle Orientation and Rotational TrackingR01GM115763 · NIGMS · GEORGIA STATE UNIVERSITY · PI FANG, NING · 2015 to 2019
$1.5M
Insights into Gordon Holmes syndrome by substrate profiling of Triad3A and Chip using Orthogonal Ubiquitin TransferR21NS116760 · NINDS · GEORGIA STATE UNIVERSITY · PI MABB, ANGELA M, YIN, JUN · 2021 to 2021
$429k
NIDA NIH HHS R01 DA041529NIGMS NIH HHS R01 GM115763NINDS NIH HHS R21 NS116760
6 · The paper itself

Abstract

Recessive mutations in

Indexed as

Biological sciencesCell biologyDiseaseFunctional aspects of cell biology

Identifiers

PMID35620441
PMCPMC9126796
OpenAlexW4280644894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.