Evidence map›Paper›PMID 35620409›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Metabolomic Mechanisms of Radix Fici Hirtae against Carbon Tetrachloride-Induced Acute Liver Damage in Mice.

Fang-Yu Zhou, Ting Quan, Shi-Jian Xiang, Hui Li, Hui-Yuan Chen, Yu-Xuan Yang, Sha-Sha Li

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Bioactive compounds fromBiochemistry and biophysics reports · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Fang-Yu ZhouDepartment of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0002-7957-2524
Ting QuanDepartment of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0003-2163-1883
Shi-Jian XiangDepartment of Pharmacy, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong, China.ORCID https://orcid.org/0000-0002-7119-5728
Hui LiDepartment of Traditional Chinese Medicine, Guangzhou Red Cross Hospital, Medicine College, Jinan University, Guangzhou 510220, China.ORCID https://orcid.org/0000-0002-6001-0652
Hui-Yuan ChenDepartment of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0002-9100-8918
Yu-Xuan YangDepartment of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0003-3332-8363
Sha-Sha LiDepartment of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0003-4346-7535
First Affiliated Hospital of Jinan University · CNJinan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radix Fici Hirtae (RFH), known as Methods: Mice fed with the water extract of RFH at a dose of 1.5 g/kg and 0.75 g/kg for consecutive 7 days, and then serum samples were taken for the metabolomic analysis. Furthermore, the bioinformatics and pathways analysis were measured. Results: The UHPLC-Orbitrap/MS based-metabolomic analysis identified 20 differential metabolic markers in serum of CCl Conclusion: These findings provide potential metabolic mechanism for future study and allow for hypothesis generation about the hepatoprotective effects of Radix Fici Hirtae.

Identifiers

PMID35620409
PMCPMC9129960
OpenAlexW4280596618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.